Merab Kokaia Experimental Epilepsy Group, Epilepsy Centre, Department of Clinical Sciences Lund University Hospital Biography Publications Institution JoVE Articles Merab Kokaia has not added a biography. If you are Merab Kokaia and would like to personalize this page please email our Author Liaison for assistance. Publications Myo-Inositol Limits Kainic Acid-Induced Epileptogenesis in Rats International Journal of Molecular Sciences. Jan, 2022 | Pubmed ID: 35163126 Human Stem Cell-Derived GABAergic Interneurons Establish Efferent Synapses Onto Host Neurons in Rat Epileptic Hippocampus and Inhibit Spontaneous Recurrent Seizures International Journal of Molecular Sciences. Dec, 2021 | Pubmed ID: 34948040 Human Stem Cell-derived GABAergic Neurons Functionally Integrate into Human Neuronal Networks Scientific Reports. 11, 2021 | Pubmed ID: 34764308 Gene Therapy Vector Encoding Neuropeptide Y and Its Receptor Y2 for Future Treatment of Epilepsy: Preclinical Data in Rats Frontiers in Molecular Neuroscience. 2020 | Pubmed ID: 33343295 Inhibition of Epileptiform Activity by Neuropeptide Y in Brain Tissue from Drug-resistant Temporal Lobe Epilepsy Patients Scientific Reports. 12, 2019 | Pubmed ID: 31852985 Disease Modification by Combinatorial Single Vector Gene Therapy: A Preclinical Translational Study in Epilepsy Molecular Therapy. Methods & Clinical Development. Dec, 2019 | Pubmed ID: 31660420 Concentration- and Time-dependent Effects of Myo-inositol on Evoked Epileptic Afterdischarge in the Hippocampus in Vivo Neuroreport. 11, 2019 | Pubmed ID: 31568207 Long-Term Effects of Myoinositol on Behavioural Seizures and Biochemical Changes Evoked by Kainic Acid Induced Epileptogenesis BioMed Research International. 2019 | Pubmed ID: 30941363 Long-Term, Targeted Delivery of GDNF from Encapsulated Cells Is Neuroprotective and Reduces Seizures in the Pilocarpine Model of Epilepsy The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. 03, 2019 | Pubmed ID: 30665947 Unilateral Ex Vivo Gene Therapy by GDNF in Epileptic Rats Gene Therapy. 04, 2019 | Pubmed ID: 30464254 Dynamic Interaction of Local and Transhemispheric Networks is Necessary for Progressive Intensification of Hippocampal Seizures Scientific Reports. 04, 2018 | Pubmed ID: 29618778 Altered Chloride Homeostasis Decreases the Action Potential Threshold and Increases Hyperexcitability in Hippocampal Neurons ENeuro. Nov-Dec, 2017 | Pubmed ID: 29379872 Directly Converted Human Fibroblasts Mature to Neurons and Show Long-Term Survival in Adult Rodent Hippocampus Stem Cells International. 2017 | Pubmed ID: 29317869 Epilepsy and Optogenetics: Can Seizures Be Controlled by Light? Clinical Science (London, England : 1979). Jul, 2017 | Pubmed ID: 28667062 Advances in the Development of Biomarkers for Epilepsy The Lancet. Neurology. Jul, 2016 | Pubmed ID: 27302363 Optogenetic Control of Human Neurons in Organotypic Brain Cultures Scientific Reports. Apr, 2016 | Pubmed ID: 27098488 Translational Approach for Gene Therapy in Epilepsy: Model System and Unilateral Overexpression of Neuropeptide Y and Y2 Receptors Neurobiology of Disease. Feb, 2016 | Pubmed ID: 26607785 Differential Effect of Neuropeptides on Excitatory Synaptic Transmission in Human Epileptic Hippocampus The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jul, 2015 | Pubmed ID: 26134645 Optogenetics Reveal Delayed Afferent Synaptogenesis on Grafted Human-induced Pluripotent Stem Cell-derived Neural Progenitors Stem Cells (Dayton, Ohio). Dec, 2014 | Pubmed ID: 25183299 Global Optogenetic Activation of Inhibitory Interneurons During Epileptiform Activity The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Feb, 2014 | Pubmed ID: 24573293 Optogenetic Inhibition of Chemically Induced Hypersynchronized Bursting in Mice Neurobiology of Disease. May, 2014 | Pubmed ID: 24491965 Encapsulated Galanin-producing Cells Attenuate Focal Epileptic Seizures in the Hippocampus Epilepsia. Jan, 2014 | Pubmed ID: 24245512 Novel Approaches to Epilepsy Treatment Epilepsia. Jan, 2013 | Pubmed ID: 23106744 An Optogenetic Approach in Epilepsy Neuropharmacology. Jun, 2013 | Pubmed ID: 22698957 VEGF Receptor-2 (Flk-1) Overexpression in Mice Counteracts Focal Epileptic Seizures PloS One. 2012 | Pubmed ID: 22808185 Light-activated Channels in Acute Seizures Epilepsia. Oct, 2011 | Pubmed ID: 21967352 Seizure-induced Neurogenesis in the Adult Brain The European Journal of Neuroscience. Mar, 2011 | Pubmed ID: 21395857 The Treatment of Neurological Diseases Under a New Light: the Importance of Optogenetics Drugs of Today (Barcelona, Spain : 1998). Jan, 2011 | Pubmed ID: 21373649 Leaky Optoelectrical Fiber for Optogenetic Stimulation and Electrochemical Detection of Dopamine Exocytosis from Human Dopaminergic Neurons Advanced Science (Weinheim, Baden-Wurttemberg, Germany). | Pubmed ID: 31871869 Transplantation of Human Stem Cell-Derived GABAergic Neurons into the Early Postnatal Mouse Hippocampus to Mitigate Neurodevelopmental Disorders Ana Gonzalez-Ramos2, Kerstin Laurin1, Fredrik Berglind1, Marco Ledri3, Merab Kokaia2, My Andersson1 1Cellular Neurophysiology and Epilepsy Group, Epilepsy Centre, Department of Clinical Sciences, Lund University Hospital, 2Experimental Epilepsy Group, Epilepsy Centre, Department of Clinical Sciences, Lund University Hospital, 3Molecular Neurophysiology and Epilepsy Group, Epilepsy Center, Department of Clinical Sciences, Lund University Hospital JoVE 64272 Neurociencia
Transplantation of Human Stem Cell-Derived GABAergic Neurons into the Early Postnatal Mouse Hippocampus to Mitigate Neurodevelopmental Disorders Ana Gonzalez-Ramos2, Kerstin Laurin1, Fredrik Berglind1, Marco Ledri3, Merab Kokaia2, My Andersson1 1Cellular Neurophysiology and Epilepsy Group, Epilepsy Centre, Department of Clinical Sciences, Lund University Hospital, 2Experimental Epilepsy Group, Epilepsy Centre, Department of Clinical Sciences, Lund University Hospital, 3Molecular Neurophysiology and Epilepsy Group, Epilepsy Center, Department of Clinical Sciences, Lund University Hospital JoVE 64272 Neurociencia
