Samantha N. Cobos Chemistry Deparment The Graduate Center of the City University of New York Biography Publications Institution JoVE Articles Samantha N. Cobos Samantha Cobos is a current student in the Ph.D. Program in Chemistry at the Graduate Center of the City University of New York. She received her undergraduate degree in Chemistry from Pace University.Ms. Cobos’ background mainly focused on investigating the binding kinetics at the interface of proteins and other small organic molecules. During her undergraduate career, she worked in the lab of Dr. Demos Athanasopoulos where she worked on molecular dynamics simulations calculating the intrinsic reaction coordinate of Diels-Alder like reactions. Additionally, with the help of Dr. Shishir Chundawat of Rutgers University in New Brunswick, she was able to further advance the labs work into the binding kinetics of cellulose I and Cellulose I-based glycan-active enzymes.Currently Ms. Cobos is interested in how protein structure and misfolding affects disease pathology in the lab of Dr. Mariana Torrente at Brooklyn College. Publications Epigenetics in Amyotrophic Lateral Sclerosis: a Role for Histone Post-translational Modifications in Neurodegenerative Disease Translational Research : the Journal of Laboratory and Clinical Medicine. 02, 2019 | Pubmed ID: 30391475 The Impact of Histone Post-translational Modifications in Neurodegenerative Diseases Biochimica Et Biophysica Acta. Molecular Basis of Disease. Oct, 2018 | Pubmed ID: 30352259 Characterizing Histone Post-translational Modification Alterations in Yeast Neurodegenerative Proteinopathy Models Seth A. Bennett1,2, Samantha N. Cobos1,3, Marcella Meykler1, Michel Fallah1, Navin Rana1, Karen Chen1, Mariana P. Torrente1,4 1Chemistry Department, Brooklyn College, 2Ph.D. Program in Biochemistry, Graduate Center of the City University of New York, 3Ph.D. Program in Chemistry, Graduate Center of the City University of New York, 4Ph.D. Programs in Chemistry, Biochemistry, and Biology, Graduate Center of the City University of New York JoVE 59104 Genética
Characterizing Histone Post-translational Modification Alterations in Yeast Neurodegenerative Proteinopathy Models Seth A. Bennett1,2, Samantha N. Cobos1,3, Marcella Meykler1, Michel Fallah1, Navin Rana1, Karen Chen1, Mariana P. Torrente1,4 1Chemistry Department, Brooklyn College, 2Ph.D. Program in Biochemistry, Graduate Center of the City University of New York, 3Ph.D. Program in Chemistry, Graduate Center of the City University of New York, 4Ph.D. Programs in Chemistry, Biochemistry, and Biology, Graduate Center of the City University of New York JoVE 59104 Genética