Stuart G. Campbell Department of Biomedical Engineering Yale University Biography Publications Institution JoVE Articles Stuart G. Campbell has not added a biography. If you are Stuart G. Campbell and would like to personalize this page please email our Author Liaison for assistance. Publications Functional and Structural Differences Between Skinned and Intact Muscle Preparations The Journal of General Physiology. Feb, 2022 | Pubmed ID: 35045156 Myofilament Glycation in Diabetes Reduces Contractility by Inhibiting Tropomyosin Movement, is Rescued by CMyBPC Domains Journal of Molecular and Cellular Cardiology. Jan, 2022 | Pubmed ID: 34487755 MicroRNA Function Can Be Reversed by Altering Target Gene Expression Levels IScience. Oct, 2021 | Pubmed ID: 34755085 Loss of Crossbridge Inhibition Drives Pathological Cardiac Hypertrophy in Patients Harboring the TPM1 E192K Mutation The Journal of General Physiology. 09, 2021 | Pubmed ID: 34319370 Danicamtiv Enhances Systolic Function and Frank-Starling Behavior at Minimal Diastolic Cost in Engineered Human Myocardium Journal of the American Heart Association. 06, 2021 | Pubmed ID: 34096321 Evidence for Synergy Between Sarcomeres and Fibroblasts in an in Vitro Model of Myocardial Reverse Remodeling Journal of Molecular and Cellular Cardiology. 09, 2021 | Pubmed ID: 33992697 Potential Impacts of the Cardiac Troponin I Mobile Domain on Myofilament Activation and Relaxation Journal of Molecular and Cellular Cardiology. 06, 2021 | Pubmed ID: 33647310 Mavacamten Preserves Length-dependent Contractility and Improves Diastolic Function in Human Engineered Heart Tissue American Journal of Physiology. Heart and Circulatory Physiology. 03, 2021 | Pubmed ID: 33449850 Fast-relaxing Cardiomyocytes Exert a Dominant Role in the Relaxation Behavior of Heterogeneous Myocardium Archives of Biochemistry and Biophysics. 01, 2021 | Pubmed ID: 33271148 Multiscale Modeling of Cardiovascular Function Predicts That the End-Systolic Pressure Volume Relationship Can Be Targeted Via Multiple Therapeutic Strategies Frontiers in Physiology. 2020 | Pubmed ID: 32973561 Contractile Work Directly Modulates Mitochondrial Protein Levels in Human Engineered Heart Tissues American Journal of Physiology. Heart and Circulatory Physiology. 06, 2020 | Pubmed ID: 32383992 Polycystin 2 is Increased in Disease to Protect Against Stress-induced Cell Death Scientific Reports. 01, 2020 | Pubmed ID: 31941974 KBTBD13 and the Ever-expanding Sarcomeric Universe The Journal of Clinical Investigation. 02, 2020 | Pubmed ID: 31904591 Modular Design of a Tissue Engineered Pulsatile Conduit Using Human Induced Pluripotent Stem Cell-derived Cardiomyocytes Acta Biomaterialia. 01, 2020 | Pubmed ID: 31634626 Modelling Sarcomeric Cardiomyopathies with Human Cardiomyocytes Derived from Induced Pluripotent Stem Cells The Journal of Physiology. 07, 2020 | Pubmed ID: 30624779 A Microwell Cell Capture Device Reveals Variable Response to Dobutamine in Isolated Cardiomyocytes Biophysical Journal. 10, 2019 | Pubmed ID: 31537313 Cardiomyocyte D-dopachrome Tautomerase Protects Against Heart Failure JCI Insight. 09, 2019 | Pubmed ID: 31484822 Extracellular Matrix From Hypertrophic Myocardium Provokes Impaired Twitch Dynamics in Healthy Cardiomyocytes JACC. Basic to Translational Science. Aug, 2019 | Pubmed ID: 31468004 Patient Mutations Linked to Arrhythmogenic Cardiomyopathy Enhance Calpain-mediated Desmoplakin Degradation JCI Insight. 06, 2019 | Pubmed ID: 31194698 The Effect of Tropomyosin Mutations on Actin-Tropomyosin Binding: In Search of Lost Time Biophysical Journal. 06, 2019 | Pubmed ID: 31130236 Sarcomere-Directed Calcium Reporters in Cardiomyocytes Circulation Research. 04, 2019 | Pubmed ID: 30973804 A Short History of the Development of Mathematical Models of Cardiac Mechanics Journal of Molecular and Cellular Cardiology. 02, 2019 | Pubmed ID: 30503754 Diverse Relaxation Rates Exist Among Rat Cardiomyocytes Isolated from a Single Myocardial Region The Journal of Physiology. 02, 2019 | Pubmed ID: 30315728 Precise Binding of Tropomyosin on Actin Involves Sequence-Dependent Variance in Coiled-Coil Twisting Biophysical Journal. 09, 2018 | Pubmed ID: 30195938 Force-Dependent Recruitment from the Myosin Off State Contributes to Length-Dependent Activation Biophysical Journal. 08, 2018 | Pubmed ID: 30054031 Skeletal Myosin Binding Protein-C Isoforms Regulate Thin Filament Activity in a Ca-dependent Manner Scientific Reports. 02, 2018 | Pubmed ID: 29422607 A Protocol for Collecting Human Cardiac Tissue for Research The VAD Journal : the Journal of Mechanical Assisted Circulation and Heart Failure. 2016 | Pubmed ID: 28042604 Low-dose Dasatinib Rescues Cardiac Function in Noonan Syndrome JCI Insight. 12, 2016 | Pubmed ID: 27942593 Acute Optogenetic Modulation of Cardiac Twitch Dynamics Explored Through Modeling Journal of Biomechanical Engineering. 11, 2016 | Pubmed ID: 27618140 Anisotropic Engineered Heart Tissue Made from Laser-cut Decellularized Myocardium Scientific Reports. 08, 2016 | Pubmed ID: 27572147 Structural Determinants of Muscle Thin Filament Cooperativity Archives of Biochemistry and Biophysics. Mar, 2016 | Pubmed ID: 26891592 Modeling Predicts a Connection Between Sinus Vortex Effects and Aortic Compliance Journal of Theoretical Biology. Jan, 2016 | Pubmed ID: 26585547 Slowing of Contractile Kinetics by Myosin-binding Protein C Can Be Explained by Its Cooperative Binding to the Thin Filament Journal of Molecular and Cellular Cardiology. 07, 2016 | Pubmed ID: 26454159 Contributions of Ca2+-Independent Thin Filament Activation to Cardiac Muscle Function Biophysical Journal. Nov, 2015 | Pubmed ID: 26588569 Prospects for In Vitro Myofilament Maturation in Stem Cell-Derived Cardiac Myocytes Biomarker Insights. 2015 | Pubmed ID: 26085788 Mathematical Modeling of Aortic Valve Dynamics During Systole Journal of Theoretical Biology. Jan, 2015 | Pubmed ID: 25451522 Decreased Polycystin 2 Expression Alters Calcium-contraction Coupling and Changes β-adrenergic Signaling Pathways Proceedings of the National Academy of Sciences of the United States of America. Nov, 2014 | Pubmed ID: 25368166 Timing and Magnitude of Systolic Stretch Affect Myofilament Activation and Mechanical Work American Journal of Physiology. Heart and Circulatory Physiology. Aug, 2014 | Pubmed ID: 24878774 इंजीनियर फेफड़ों के ऊतकों को विकोशिकीय फेफड़ों के स्लाइस से तैयार किया जाता है Katherine L. Leiby1,2, Ronald Ng1, Stuart G. Campbell1,3, Laura E. Niklason1,4 1Department of Biomedical Engineering, Yale University, 2Yale School of Medicine, 3Department of Cellular and Molecular Physiology, Yale School of Medicine, 4Department of Anesthesiology, Yale School of Medicine JoVE 63151 Bioingeniería
इंजीनियर फेफड़ों के ऊतकों को विकोशिकीय फेफड़ों के स्लाइस से तैयार किया जाता है Katherine L. Leiby1,2, Ronald Ng1, Stuart G. Campbell1,3, Laura E. Niklason1,4 1Department of Biomedical Engineering, Yale University, 2Yale School of Medicine, 3Department of Cellular and Molecular Physiology, Yale School of Medicine, 4Department of Anesthesiology, Yale School of Medicine JoVE 63151 Bioingeniería
