Tetsushi Furukawa Department of Bio-informational Pharmacology, Medical Research Institute Tokyo Medical and Dental University Biography Publications Institution JoVE Articles Tetsushi Furukawa has not added a biography. If you are Tetsushi Furukawa and would like to personalize this page please email our Author Liaison for assistance. Publications Combined Analysis of Human and Experimental Murine Samples Identified Novel Circulating MicroRNAs As Biomarkers for Atrial Fibrillation Circulation Journal : Official Journal of the Japanese Circulation Society. Feb, 2018 | Pubmed ID: 29398686 Flecainide Ameliorates Arrhythmogenicity Through NCX Flux in Andersen-Tawil Syndrome-iPS Cell-derived Cardiomyocytes Biochemistry and Biophysics Reports. Mar, 2017 | Pubmed ID: 28956012 Calcification of Joints and Arteries with Novel NT5E Mutations with Involvement of Upper Extremity Arteries Vascular Medicine (London, England). 12, 2017 | Pubmed ID: 28825389 Association of the Clinical and Genetic Factors With Superior Vena Cava Arrhythmogenicity in Atrial Fibrillation Circulation Journal : Official Journal of the Japanese Circulation Society. Dec, 2017 | Pubmed ID: 28804107 Chromosome 4q25 Variants and Recurrence After Second-generation Cryoballoon Ablation in Patients with Paroxysmal Atrial Fibrillation International Journal of Cardiology. Oct, 2017 | Pubmed ID: 28637626 Overexpression of KCNJ2 in Induced Pluripotent Stem Cell-derived Cardiomyocytes for the Assessment of QT-prolonging Drugs Journal of Pharmacological Sciences. Jun, 2017 | Pubmed ID: 28615142 Identification of Six New Genetic Loci Associated with Atrial Fibrillation in the Japanese Population Nature Genetics. Jun, 2017 | Pubmed ID: 28416822 Genetic Variants Associated With Susceptibility to Atrial Fibrillation in a Japanese Population The Canadian Journal of Cardiology. Apr, 2017 | Pubmed ID: 28129963 Clinical Utility and Functional Analysis of Variants in Atrial Fibrillation-associated Locus 4q25 Journal of Cardiology. Oct, 2017 | Pubmed ID: 28087289 Association of ZFHX3 Gene Variation with Atrial Fibrillation, Cerebral Infarction, and Lung Thromboembolism: An Autopsy Study Journal of Cardiology. Aug, 2017 | Pubmed ID: 28007413 IRX3 Variant As a Modifier of Brugada Syndrome with Frequent Ventricular Fibrillation HeartRhythm Case Reports. Nov, 2016 | Pubmed ID: 28491738 [Therapeutic Strategy Targeting Membrane Molecular Meshanosensing.] Clinical Calcium. 2016 | Pubmed ID: 27885185 Embryonic Type Nachannel β-subunit, SCN3B Masks the Disease Phenotype of Brugada Syndrome Scientific Reports. Sep, 2016 | Pubmed ID: 27677334 Sex Hormonal Regulation of Cardiac Ion Channels in Drug-induced QT Syndromes Pharmacology & Therapeutics. Dec, 2016 | Pubmed ID: 27595633 Long-Term Prognosis of Catecholaminergic Polymorphic Ventricular Tachycardia Patients With Ryanodine Receptor (RYR2) Mutations Circulation Journal : Official Journal of the Japanese Circulation Society. Aug, 2016 | Pubmed ID: 27523319 Novel Dielectric Coagulometer Identifies Hypercoagulability in Patients with a High CHADS2 Score Without Atrial Fibrillation PloS One. 2016 | Pubmed ID: 27275926 A Distribution Analysis of Action Potential Parameters Obtained from Patch-clamped Human Stem Cell-derived Cardiomyocytes Journal of Pharmacological Sciences. Jun, 2016 | Pubmed ID: 27179939 Oxidative Stress Induced Ventricular Arrhythmia and Impairment of Cardiac Function in Nos1ap Deleted Mice International Heart Journal. May, 2016 | Pubmed ID: 27170476 Sall1 Transiently Marks Undifferentiated Heart Precursors and Regulates Their Fate Journal of Molecular and Cellular Cardiology. Mar, 2016 | Pubmed ID: 26876450 Intravital Imaging of Ca(2+) Signals in Lymphocytes of Ca(2+) Biosensor Transgenic Mice: Indication of Autoimmune Diseases Before the Pathological Onset Scientific Reports. Jan, 2016 | Pubmed ID: 26732477 High-fat Diet Increases Vulnerability to Atrial Arrhythmia by Conduction Disturbance Via MiR-27b Journal of Molecular and Cellular Cardiology. Jan, 2016 | Pubmed ID: 26654778 Genetic Defects in a His-Purkinje System Transcription Factor, IRX3, Cause Lethal Cardiac Arrhythmias European Heart Journal. May, 2016 | Pubmed ID: 26429810 Screening System for Drug-induced Arrhythmogenic Risk Combining a Patch Clamp and Heart Simulator Science Advances. May, 2015 | Pubmed ID: 26601174 Enhancement of Spontaneous Activity by HCN4 Overexpression in Mouse Embryonic Stem Cell-Derived Cardiomyocytes - A Possible Biological Pacemaker PloS One. 2015 | Pubmed ID: 26384234 Severe Iatrogenic Bradycardia Related to the Combined Use of Beta-blocking Agents and Sodium Channel Blockers Clinical Pharmacology : Advances and Applications. 2015 | Pubmed ID: 25733934 Endothelin-1 Induces Myofibrillar Disarray and Contractile Vector Variability in Hypertrophic Cardiomyopathy-induced Pluripotent Stem Cell-derived Cardiomyocytes Journal of the American Heart Association. Dec, 2014 | Pubmed ID: 25389285 Image-based Evaluation of Contraction-relaxation Kinetics of Human-induced Pluripotent Stem Cell-derived Cardiomyocytes: Correlation and Complementarity with Extracellular Electrophysiology Journal of Molecular and Cellular Cardiology. Dec, 2014 | Pubmed ID: 25257913 Integrating Genetic, Transcriptional, and Functional Analyses to Identify 5 Novel Genes for Atrial Fibrillation Circulation. Oct, 2014 | Pubmed ID: 25124494 Non-genomic Action of Sex Steroid Hormones and Cardiac Repolarization Biological & Pharmaceutical Bulletin. 2013 | Pubmed ID: 23302631 Effects of an HERG Activator, ICA-105574, on Electrophysiological Properties of Canine Hearts Journal of Pharmacological Sciences. 2013 | Pubmed ID: 23238536 Stretch of Atrial Myocytes Stimulates Recruitment of Macrophages Via ATP Released Through Gap-junction Channels Journal of Pharmacological Sciences. 2012 | Pubmed ID: 23196902 Sex and Gender Aspects in Antiarrhythmic Therapy Handbook of Experimental Pharmacology. 2012 | Pubmed ID: 23027454 Meta-Analyse Identifiziert Sechs Neue Anfälligkeit Loci Für Vorhofflimmern Nature Genetics. Jun, 2012 | Pubmed ID: 22544366 [Atrial Fibrillation and Inflammation] Nihon Yakurigaku Zasshi. Folia Pharmacologica Japonica. Nov, 2011 | Pubmed ID: 22075461 Circulating KCNH2 Current-activating Factor in Patients with Heart Failure and Ventricular Tachyarrhythmia PloS One. 2011 | Pubmed ID: 21625547 Acute Effects of Sex Steroid Hormones on Susceptibility to Cardiac Arrhythmias: a Simulation Study PLoS Computational Biology. Jan, 2010 | Pubmed ID: 20126530 A Genetically Encoded Bioluminescent Indicator for the Sodium Channel Activity in Living Cells Journal of the American Chemical Society. Apr, 2009 | Pubmed ID: 19271706 New Aspects for the Treatment of Cardiac Diseases Based on the Diversity of Functional Controls on Cardiac Muscles: Acute Effects of Female Hormones on Cardiac Ion Channels and Cardiac Repolarization Journal of Pharmacological Sciences. Mar, 2009 | Pubmed ID: 19270425 A Receptor-independent Effect of Estrone Sulfate on the HERG Channel Journal of Pharmacological Sciences. Jan, 2009 | Pubmed ID: 19129680 Redox- and Calmodulin-dependent S-nitrosylation of the KCNQ1 Channel The Journal of Biological Chemistry. Feb, 2009 | Pubmed ID: 19124472 KCNE Variants Reveal a Critical Role of the Beta Subunit Carboxyl Terminus in PKA-dependent Regulation of the IKs Potassium Channel Channels (Austin, Tex.). Jan-Feb, 2009 | Pubmed ID: 19077539 A Combined Approach Using Patch-Clamp Study and Computer Simulation Study for Understanding Long QT Syndrome and TdP in Women Current Cardiology Reviews. Nov, 2008 | Pubmed ID: 20066131 Non-genomic Regulation of Cardiac Ion Channels by Sex Hormones Cardiovascular & Hematological Disorders Drug Targets. Dec, 2008 | Pubmed ID: 19075634 Bioluminescent Indicators for Ca2+ Based on Split Renilla Luciferase Complementation in Living Cells Analytical Sciences : the International Journal of the Japan Society for Analytical Chemistry. 2008 | Pubmed ID: 18997366 Acute Effects of Oestrogen on the Guinea Pig and Human IKr Channels and Drug-induced Prolongation of Cardiac Repolarization The Journal of Physiology. Jun, 2008 | Pubmed ID: 18440994 High Glucose Concentrations Impair the Activation of K+ Channels and Proteases in Undifferentiated THP-1 Monocytes Journal of Medical and Dental Sciences. Mar, 2007 | Pubmed ID: 19845141 Regulation of Cardiac Ion Channels Via Non-genomic Action of Sex Steroid Hormones: Implication for the Gender Difference in Cardiac Arrhythmias Pharmacology & Therapeutics. Jul, 2007 | Pubmed ID: 17583354 T75M-KCNJ2 Mutation Causing Andersen-Tawil Syndrome Enhances Inward Rectification by Changing Mg2+ Sensitivity Journal of Molecular and Cellular Cardiology. Aug, 2007 | Pubmed ID: 17582433 Ginsenoside Re, a Main Phytosterol of Panax Ginseng, Activates Cardiac Potassium Channels Via a Nongenomic Pathway of Sex Hormones Molecular Pharmacology. Dec, 2006 | Pubmed ID: 16985185 Potassium Channel Remodeling in Cardiac Hypertrophy Journal of Molecular and Cellular Cardiology. Nov, 2006 | Pubmed ID: 16962130 Nontranscriptional Regulation of Cardiac Repolarization Currents by Testosterone Circulation. Sep, 2005 | Pubmed ID: 16157773 Role of Nitric Oxide in Ca2+ Sensitivity of the Slowly Activating Delayed Rectifier K+ Current in Cardiac Myocytes Circulation Research. Jan, 2005 | Pubmed ID: 15569827 Aquaporin-2 Trafficking is Regulated by PDZ-domain Containing Protein SPA-1 FEBS Letters. Jun, 2004 | Pubmed ID: 15196935 Block of HERG Current Expressed in HEK293 Cells by the Na+-channel Blocker Cibenzoline Heart and Vessels. May, 2004 | Pubmed ID: 15168062 Nitric Oxide-dependent Modulation of the Delayed Rectifier K+ Current and the L-type Ca2+ Current by Ginsenoside Re, an Ingredient of Panax Ginseng, in Guinea-pig Cardiomyocytes British Journal of Pharmacology. Jun, 2004 | Pubmed ID: 15148247 [Various Functions of ClC-type Cl- Channels] Nihon Yakurigaku Zasshi. Folia Pharmacologica Japonica. Nov, 2003 | Pubmed ID: 14569156 The Mouse Sino-atrial Node Expresses Both the Type 2 and Type 3 Ca(2+) Release Channels/ryanodine Receptors FEBS Letters. Oct, 2003 | Pubmed ID: 14550562 Electrophysiological Effects of Ginseng and Ginsenoside Re in Guinea Pig Ventricular Myocytes European Journal of Pharmacology. Aug, 2003 | Pubmed ID: 12969747 Ion Channel Remodeling in Cardiac Hypertrophy is Prevented by Blood Pressure Reduction Without Affecting Heart Weight Increase in Rats with Abdominal Aortic Banding Journal of Cardiovascular Pharmacology. Jun, 2002 | Pubmed ID: 12021581 Functional Modulation of Cardiac ATP-Sensitive K(+) Channels News in Physiological Sciences : an International Journal of Physiology Produced Jointly by the International Union of Physiological Sciences and the American Physiological Society. Jun, 1998 | Pubmed ID: 11390776 Elektrophysiologische Bewertung der murinen Atria mit hochauflösenden optischen Mapping Kensuke Ihara*1, Koji Sugiyama*1, Kentaro Takahashi*1, Masahiro Yamazoe1, Tetsuo Sasano2, Tetsushi Furukawa1 1Department of Bio-informational Pharmacology, Medical Research Institute, Tokyo Medical and Dental University, 2Department of Biofunctional Informatics, Tokyo Medical and Dental University JoVE 56478 Medicina
Elektrophysiologische Bewertung der murinen Atria mit hochauflösenden optischen Mapping Kensuke Ihara*1, Koji Sugiyama*1, Kentaro Takahashi*1, Masahiro Yamazoe1, Tetsuo Sasano2, Tetsushi Furukawa1 1Department of Bio-informational Pharmacology, Medical Research Institute, Tokyo Medical and Dental University, 2Department of Biofunctional Informatics, Tokyo Medical and Dental University JoVE 56478 Medicina