Xiao-Yu Tian School of Biomedical Sciences, Institute of Vascular Medicine, Li Ka Shing Institute of Health Sciences Chinese University of Hong Kong Biography Publications Institution JoVE Articles Xiao-Yu Tian has not added a biography. If you are Xiao-Yu Tian and would like to personalize this page please email our Author Liaison for assistance. Publications Uncoupling Protein 2 in Cardiovascular Health and Disease Frontiers in Physiology. 2018 | Pubmed ID: 30116205 Regulatory T Cells Promote Apelin-Mediated Sprouting Angiogenesis in Type 2 Diabetes Cell Reports. Aug, 2018 | Pubmed ID: 30089270 Recent Advances in Managing Atherosclerosis Via Nanomedicine Small (Weinheim an Der Bergstrasse, Germany). Jan, 2018 | Pubmed ID: 29239134 Inhibition of MiR-92a Suppresses Oxidative Stress and Improves Endothelial Function by Upregulating Heme Oxygenase-1 in Db/db Mice Antioxidants & Redox Signaling. 02, 2018 | Pubmed ID: 28683566 Comprehensive Analysis of Acylcarnitine Species in Db/db Mouse Using a Novel Method of High-Resolution Parallel Reaction Monitoring Reveals Widespread Metabolic Dysfunction Induced by Diabetes Analytical Chemistry. Oct, 2017 | Pubmed ID: 28859482 Generation of Human Liver Chimeric Mice with Hepatocytes from Familial Hypercholesterolemia Induced Pluripotent Stem Cells Stem Cell Reports. 03, 2017 | Pubmed ID: 28262545 Myeloid Deletion Increases Monocyte Recruitment and Worsens Atherosclerosis FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. 03, 2017 | Pubmed ID: 27927724 PPARδ Is Required for Exercise to Attenuate Endoplasmic Reticulum Stress and Endothelial Dysfunction in Diabetic Mice Diabetes. 02, 2017 | Pubmed ID: 27856609 Integrin-YAP/TAZ-JNK Cascade Mediates Atheroprotective Effect of Unidirectional Shear Flow Nature. Dec, 2016 | Pubmed ID: 27926730 Reactive Oxygen Species, Endoplasmic Reticulum Stress and Mitochondrial Dysfunction: The Link with Cardiac Arrhythmogenesis Frontiers in Physiology. 2016 | Pubmed ID: 27536244 Melamine Impairs Renal and Vascular Function in Rats Scientific Reports. 06, 2016 | Pubmed ID: 27324576 E-selectin-targeting Delivery of MicroRNAs by Microparticles Ameliorates Endothelial Inflammation and Atherosclerosis Scientific Reports. Mar, 2016 | Pubmed ID: 26956647 Bone Morphogenic Protein 4-Smad-Induced Upregulation of Platelet-Derived Growth Factor AA Impairs Endothelial Function Arteriosclerosis, Thrombosis, and Vascular Biology. Mar, 2016 | Pubmed ID: 26769046 Chronic Black Tea Extract Consumption Improves Endothelial Function in Ovariectomized Rats European Journal of Nutrition. Aug, 2016 | Pubmed ID: 26276555 A Revisit on the Renin-angiotensin System in Cardiovascular Biology Trends in Cardiovascular Medicine. Apr, 2016 | Pubmed ID: 26212445 Black Tea Protects Against Hypertension-associated Endothelial Dysfunction Through Alleviation of Endoplasmic Reticulum Stress Scientific Reports. May, 2015 | Pubmed ID: 25976123 Upregulation of Angiotensin (1-7)-Mediated Signaling Preserves Endothelial Function Through Reducing Oxidative Stress in Diabetes Antioxidants & Redox Signaling. Oct, 2015 | Pubmed ID: 25867182 Unconjugated Bilirubin Mediates Heme Oxygenase-1-induced Vascular Benefits in Diabetic Mice Diabetes. May, 2015 | Pubmed ID: 25475440 The Peroxisome Proliferator-activated Receptors in Cardiovascular Diseases: Experimental Benefits and Clinical Challenges British Journal of Pharmacology. Dec, 2015 | Pubmed ID: 25438608 Rosiglitazone Attenuated Endothelin-1-Induced Vasoconstriction of Pulmonary Arteries in the Rat Model of Pulmonary Arterial Hypertension Via Differential Regulation of ET-1 Receptors PPAR Research. 2014 | Pubmed ID: 24701204 Metformin Protects Endothelial Function in Diet-induced Obese Mice by Inhibition of Endoplasmic Reticulum Stress Through 5' Adenosine Monophosphate-activated Protein Kinase-peroxisome Proliferator-activated Receptor δ Pathway Arteriosclerosis, Thrombosis, and Vascular Biology. Apr, 2014 | Pubmed ID: 24482374 Uncoupling Protein-2 Mediates DPP-4 Inhibitor-induced Restoration of Endothelial Function in Hypertension Through Reducing Oxidative Stress Antioxidants & Redox Signaling. Oct, 2014 | Pubmed ID: 24328731 Inhibition of Bone Morphogenic Protein 4 Restores Endothelial Function in Db/db Diabetic Mice Arteriosclerosis, Thrombosis, and Vascular Biology. Jan, 2014 | Pubmed ID: 24202302 Pleiotropic Effects of Peroxisome Proliferator-activated Receptor γ and δ in Vascular Diseases Circulation Journal : Official Journal of the Japanese Circulation Society. 2013 | Pubmed ID: 24107399 Boldine Improves Endothelial Function in Diabetic Db/db Mice Through Inhibition of Angiotensin II-mediated BMP4-oxidative Stress Cascade British Journal of Pharmacology. Nov, 2013 | Pubmed ID: 23992296 Menthol Relaxes Rat Aortae, Mesenteric and Coronary Arteries by Inhibiting Calcium Influx European Journal of Pharmacology. Feb, 2013 | Pubmed ID: 23380688 Fo Shou San, an Ancient Chinese Herbal Decoction, Protects Endothelial Function Through Increasing Endothelial Nitric Oxide Synthase Activity PloS One. 2012 | Pubmed ID: 23284736 PPARδ Activation Protège La Fonction Endothéliale Chez Des Souris Diabétiques Diabetes. Dec, 2012 | Pubmed ID: 22933110 Sitagliptine D'inhibiteur De La Dipeptidyl Peptidase 4 Protège La Fonction Endothéliale Dans L'hypertension Grâce à Un Mécanisme De 1 Dépendant Le Glucagon-like Peptide Hypertension. Sep, 2012 | Pubmed ID: 22868389 La Consommation De Jus De Canneberge Chronique Restaure Les Profils De Cholestérol Et Améliore La Fonction Endothéliale Chez Ovariectomisées European Journal of Nutrition. Jul, 2012 | Pubmed ID: 22836513 Capsaicinoids Abaisser Le Cholestérol Plasmatique Et Améliorer La Fonction Endothéliale Chez Les Hamsters European Journal of Nutrition. Mar, 2012 | Pubmed ID: 22466858 NaHS Détend Artère Cérébrale De Rat in Vitro Par L'inhibition Des Canaux De Type L Sensibles à La Tension Ca(2+) Pharmacological Research : the Official Journal of the Italian Pharmacological Society. Feb, 2012 | Pubmed ID: 22133671 OS De Protéine Morphogénique-4 Induit L'apoptose Des Cellules Endothéliales Par P38MAPK De Dépendante De Stress Oxydatif Et De La Voie De JNK Journal of Molecular and Cellular Cardiology. Jan, 2012 | Pubmed ID: 22064324 Le Raloxifène Améliore La Réactivité Vasculaire Dans Les Artères Coronaires Septales Pressurisés De Rates Ovariectomisées Hamsters Nourries De Cholestérol Pharmacological Research : the Official Journal of the Italian Pharmacological Society. Feb, 2012 | Pubmed ID: 22005391 Oxydatif Prostaglandine F Stress-dépendante Cyclooxygenase-2-dérivée (2α) Altère La Fonction Endothéliale Chez Des Rats Hypertendus Rénovasculaires Antioxidants & Redox Signaling. Feb, 2012 | Pubmed ID: 21951274 Endothélial D'oxyde Nitrique Synthase Enhancer Réduit Le Stress Oxydatif Et Restaure La Fonction Endothéliale Chez Les Souris Db/db Cardiovascular Research. Nov, 2011 | Pubmed ID: 21875904 L'adiponectine Est Requise Pour PPARγ Médiée Par Amélioration De La Fonction Endothéliale Chez Des Souris Diabétiques Cell Metabolism. Jul, 2011 | Pubmed ID: 21723508 Effet De Phytostérols Et De Leurs Produits D'oxydation Sur Les Profils De Lipoprotéines Et La Fonction Vasculaire Du Hamster Nourris Avec Un Régime Riche En Cholestérol Atherosclerosis. Nov, 2011 | Pubmed ID: 21719014 L'inhibition Du Système Rénine-angiotensine Inverse La Dysfonction Endothéliale Et Du Stress Oxydatif Chez Les Rats Déficients D'oestrogène PloS One. 2011 | Pubmed ID: 21479266 AVE3085, Un Activateur De Monoxyde D'azote Synthase Endothéliale, Restaure La Fonction Endothéliale Et Réduit La Pression Artérielle Chez Des Rats Spontanément Hypertendus British Journal of Pharmacology. Jul, 2011 | Pubmed ID: 21385179 Telmisartan Inhibe La Vasoconstriction Via Expression PPARγ-dépendante Et Activation Du Monoxyde D'azote Synthase Endothéliale Cardiovascular Research. Apr, 2011 | Pubmed ID: 21156825 Prostaglandines Dans Rôles Indispensable De L'action De La Cyclo-oxygénase-1 Et -2 Endothélium-dépendante Des Contractions Advances in Pharmacology (San Diego, Calif.). 2010 | Pubmed ID: 21081215 OS De Protéine Morphogénique-4 Altère La Fonction Endothéliale Via L'upregulation De Cyclooxygenase-2 Dépendante De Stress Oxydative : Incidences Sur L'hypertension Circulation Research. Oct, 2010 | Pubmed ID: 20724703 Canaux K + 4-aminopyridine Sensibles Contribue à L'hyperpolarisation De La Membrane Induite Par NaHS Et Relaxation Dans L'artère Coronaire De Rat Vascular Pharmacology. Sep-Oct, 2010 | Pubmed ID: 20430111 La Dysfonction Endothéliale : La Conséquence Commune Dans Le Diabète Et L'hypertension Journal of Cardiovascular Pharmacology. Apr, 2010 | Pubmed ID: 20422734 Stress Oxydatif De L'angiotensine II De Type 1 Récepteur Dépendant Intervient Dans La Dysfonction Endothéliale Chez Des Souris Diabétiques De Type 2 Antioxidants & Redox Signaling. Sep, 2010 | Pubmed ID: 20136508 Un modèle de souris chimériques du foie humain de l’hypercholestérolémie utilisant des hépatocytes de dérivés de cellules souches pluripotentes induites Jiayin Yang*1,2,6, Lai-Yung Wong*2, Xiao-Yu Tian*3, Rui Wei1,2, Wing-Hon Lai2, Ka-Wing Au2, Zhiwei Luo4,5, Carl Ward4,5, Wai-In Ho2, David P. Ibañez4,5, Hao Liu4,5, Xichen Bao4,5, Baoming Qin4,5, Yu Huang3, Miguel A. Esteban4,5,7, Hung-Fat Tse1,2,6,7 1Department of Medicine, University of Hong Kong-Shenzhen Hospital, 2The Cardiology Division, Department of Medicine, Li Ka Shing Faculty of Medicine, University of Hong Kong, 3School of Biomedical Sciences, Institute of Vascular Medicine, Li Ka Shing Institute of Health Sciences, Chinese University of Hong Kong, 4Key Laboratory of Regenerative Biology of the Chinese Academy of Sciences, Joint School of Life Sciences, Guangzhou Institutes of Biomedicine and Health and Guangzhou Medical University, 5Laboratory of RNA, Chromatin, and Human Disease, CAS Key Laboratory of Regenerative Biology and Guangdong Provincial Key Laboratory of Stem Cells and Regenerative Medicine, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, 6Research Centre of Heart, Brain, Hormone, and Healthy Ageing, Li Ka Shing Faculty of Medicine, University of Hong Kong, 7Hong Kong-Guangdong Stem Cell and Regenerative Medicine Research Centre, University of Hong Kong and Guangzhou Institutes of Biomedicine and Health JoVE 57556 Biología del desarrollo
Un modèle de souris chimériques du foie humain de l’hypercholestérolémie utilisant des hépatocytes de dérivés de cellules souches pluripotentes induites Jiayin Yang*1,2,6, Lai-Yung Wong*2, Xiao-Yu Tian*3, Rui Wei1,2, Wing-Hon Lai2, Ka-Wing Au2, Zhiwei Luo4,5, Carl Ward4,5, Wai-In Ho2, David P. Ibañez4,5, Hao Liu4,5, Xichen Bao4,5, Baoming Qin4,5, Yu Huang3, Miguel A. Esteban4,5,7, Hung-Fat Tse1,2,6,7 1Department of Medicine, University of Hong Kong-Shenzhen Hospital, 2The Cardiology Division, Department of Medicine, Li Ka Shing Faculty of Medicine, University of Hong Kong, 3School of Biomedical Sciences, Institute of Vascular Medicine, Li Ka Shing Institute of Health Sciences, Chinese University of Hong Kong, 4Key Laboratory of Regenerative Biology of the Chinese Academy of Sciences, Joint School of Life Sciences, Guangzhou Institutes of Biomedicine and Health and Guangzhou Medical University, 5Laboratory of RNA, Chromatin, and Human Disease, CAS Key Laboratory of Regenerative Biology and Guangdong Provincial Key Laboratory of Stem Cells and Regenerative Medicine, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, 6Research Centre of Heart, Brain, Hormone, and Healthy Ageing, Li Ka Shing Faculty of Medicine, University of Hong Kong, 7Hong Kong-Guangdong Stem Cell and Regenerative Medicine Research Centre, University of Hong Kong and Guangzhou Institutes of Biomedicine and Health JoVE 57556 Biología del desarrollo