Flexible Protein Regions and Binding

Intrinsically disordered proteins are proteins that do not fold into one fixed three-dimensional shape. Their flexible structure helps them work with ordered proteins to do jobs that rigid proteins cannot easily do. They are found more often in eukaryotes than in prokaryotes, and they can be fully disordered or made of both ...

Las proteínas a menudo tienen estructuras secundarias y terciarias rígidas que pueden determinarse experimentalmente; sin embargo, muchas proteínas tienen estructuras flexibles sin una conformación fija.

Estas proteínas intrínsecamente desordenadas, o IDP, deben cambiar de forma para realizar sus funciones en un organismo.

Las sec...