Piezoelectric Dispensing
Piezoelectric Dispensing - Related Videos
07:05
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Cited by 6 •
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A Cartesian bioprinter was designed and fabricated to allow multi-material deposition in precise, reproducible geometries, while also allowing control of environmental factors. Utilizing the three-dimensional bioprinter, complex and viable constructs may be printed and easily reproduced.
07:44
Characterization of Full Set Material Constants and Their Temperature Dependence for Piezoelectric Materials Using Resonant Ultrasound Spectroscopy
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This protocol describes the procedure of measuring the temperature dependence of the full set material constants of piezoelectric materials using resonant ultrasound spectroscopy (RUS).
10:14
Automated Robotic Dispensing Technique for Surface Guidance and Bioprinting of Cells
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Cited by 9 •
2016
This protocol describes a bioprinting methodology using an automated robotic depositing system that incorporates etched topographical guidance cues with the precision deposition of a cell bearing hydrogel bioink. The printed cells are directly delivered to the etched features and are able to sense and orientate with them.
10:39
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Cited by 4 •
2016
One-step fabrication method for obtaining freestanding epitaxial double heterostructure is presented. This approach could achieve ZnO coverage with a higher number density than that of the epitaxial single heterostructure, leading to a piezoelectric nanogenerator with an increased output electrical performance.
08:06
Automated Acoustic Dispensing for the Serial Dilution of Peptide Agonists in Potency Determination Assays
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Cited by 1 •
2016
Peptide adsorption to plasticware during traditional tip-based serial dilutions can significantly impact potency determination and confound the understanding of structure-activity relationships used for lead identification and lead optimization phases of drug discovery. Here methods for automated acoustic non-contact serial dilution of peptide samples are described.
FAQs
Voltage determines the extent of mechanical deformation in the piezoelectric actuator, while pulse shape influences the timing and strength of the resulting pressure pulse. Together, these electrical settings affect how much liquid leaves the nozzle and where it is deposited. Adjusting them allows researchers to tune droplet size and placement for patterned bioengineering fabrication.
Fluid properties influence how the pressure pulse is converted into a droplet as liquid moves through the nozzle. Consequently, the same actuator settings may not produce identical deposition behavior for different biological reagents, proteins, biomaterials, or cell-containing liquids. Considering the fluid alongside voltage and pulse shape helps maintain the intended volume and spatial pattern.
An applied voltage first causes the piezoelectric actuator to expand or contract. That deformation generates a pressure pulse in the liquid, which drives fluid toward and through the nozzle. The resulting ejection links electrical control to liquid placement, allowing the deposition process to be adjusted without physically contacting the receiving surface.
A basic setup requires controlling the piezoelectric actuator through an applied voltage and selecting an appropriate pulse shape. Researchers also account for the properties of the liquid and regulate where the nozzle places each droplet. Coordinating these variables supports repeatable patterned deposition of biomaterials, cells, proteins, and other biological reagents.
Noncontact operation allows droplets to be placed without direct contact between the dispensing mechanism and the receiving material. This supports controlled delivery of biological substances while minimizing material waste. The combination is useful when researchers need localized, patterned deposition for tissue engineering, diagnostic devices, biosensors, or microscale biological experiments.
Its controlled droplet size and placement support several bioengineering uses, including patterned biomaterial fabrication, delivery of cells and proteins, tissue engineering, diagnostic devices, biosensors, and microscale biological experimentation. These applications rely on placing biological materials in defined locations, making the technique relevant wherever spatial control and reduced material waste are important.