Autosampler System
Autosampler System - Related Videos
07:11
Automated HPLC Separation Using LC-Mate: An Integrated Repetitive Autosampler and Fraction Collector for Microscale Purification
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2026
An integrated autosampler and fraction collector (LC-mate) was developed to automate repetitive HPLC separations. Compatible with HPLC detectors that output analog signals, LC-mate enhances the performance of manually operated systems and accelerates research workflows that depend on high-performance liquid chromatography.
05:21
Surface Plasmon Resonance to Study Biomolecular Interactions Using a Sensor Chip
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2025
This video describes the surface plasmon resonance, or SPR, technique for studying the interaction between two molecules using a sensor chip. The change in resonance angle and the intensity of the reflected light are detected as a function of the association and dissociation of two molecules, and this provides information about the interactions between the two molecules.
10:41
Carbon and Nitrogen Analysis of Environmental Samples
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2023
Source: Laboratories of Margaret Workman and Kimberly Frye - Depaul University Elemental Analysis is a method used to determine elemental composition of a material. In environmental samples such as soils, scientists are particularly interested in the amounts of two ecologically important elements, nitrogen and carbon. Elemental analysis by the flash combustion technique works by oxidizing the sample with a catalyst through combustion in a high-temperature chamber. The products of combustion are...
09:26
Species Determination and Quantitation in Mixtures Using MRM Mass Spectrometry of Peptides Applied to Meat Authentication
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Cited by 4 •
2016
We present a protocol for identifying and quantifying the components in mixtures of species possessing similar proteins. Mass spectrometry detects peptides for identification, and gives relative quantitation by ratios of peak areas. As a tool food for fraud detection, the method can detect 1% horse in beef.
09:22
Gas Chromatography (GC) with Flame-Ionization Detection
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2023
Source: Laboratory of Dr. B. Jill Venton - University of Virginia Gas chromatography (GC) is used to separate and detect small molecular weight compounds in the gas phase. The sample is either a gas or a liquid that is vaporized in the injection port. Typically, the compounds analyzed are less than 1,000 Da, because it is difficult to vaporize larger compounds. GC is popular for environmental monitoring and industrial applications because it is very reliable and can be run nearly continuously.
FAQs
Consistency comes from coordinating sample positioning, volume aspiration, and introduction according to a programmed sequence. Because each container is handled through the same ordered stages, the system reduces variation associated with repeated manual transfers. Controlled timing and operating conditions further support comparable injections when many samples are analyzed in one chemistry workflow.
The container holds an individual sample, while the probe or syringe aspirates the defined volume required for analysis. The programmed sequence determines which container is accessed and when the sample is introduced. Together, these components connect sample identification, volume control, and timing, helping the analytical device receive samples in a reproducible order.
Controlled timing and operating conditions help make each introduction comparable across a sample set. This matters because the sample enters a separation or detection system under a planned sequence rather than through variable manual handling. In chemistry, that coordination supports consistent measurements and helps the system process complex sets without unnecessary interruptions.
A typical workflow begins with arranging samples in vials or other containers and assigning their analysis sequence. The system then positions each container, aspirates a defined volume through a probe or syringe, and introduces it into the analytical device. The same cycle continues under programmed timing and operating conditions for the remaining samples.
In chromatography and spectroscopy, the system supplies prepared samples to the relevant separation or detection device in a controlled sequence. For chromatography, this supports repeated injections into a separation workflow; for spectroscopy, it supports consistent sample delivery for measurement. The shared benefit is efficient handling of many samples with reduced manual intervention.
It is especially useful when a laboratory must analyze many samples or a complex sample set with consistent handling. Automated positioning and defined-volume transfer can reduce manual workload, lower contamination risk, and improve measurement reproducibility. These characteristics make the approach relevant to high-throughput chemistry workflows where repeated sample introduction would otherwise consume substantial analyst time.