Surface Engineering

Surface engineering is the deliberate design and modification of a material’s outermost layers to control how it interacts with its surroundings, while preserving the bulk properties beneath. In chemistry, it works by changing surface composition, structure, or energy through processes such as adsorption, chemical functionalization, coating, deposition, or plasma treatment; these changes can alter wettability, adhesion, reactivity, and resistance to corrosion or wear. The resulting surfaces support applications in catalysis, sensors, separations, energy technologies, biomedical materials, and manufacturing, where interfacial behavior often determines performance. Understanding surface engineering therefore links molecular-scale chemistry with practical control of durability, selectivity, and compatibility.

Surface Engineering - Related Videos

Research

JoVE Journal - Bioengineering

ECM Protein Nanofibers and Nanostructures Engineered Using Surface-initiated Assembly

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Cited by 17 •

2014

A method to obtain nanofibers and complex nanostructures from single or multiple extracellular matrix proteins is described. This method uses protein-surface interactions to create free-standing protein-based materials with tunable composition and architecture for use in a variety of tissue engineering and biotechnology applications.

Preparation of Thermoresponsive Nanostructured Surfaces for Tissue Engineering

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Cited by 5 •

2016

Nanoscaled sea-island surfaces composed of thermoresponsive block copolymers were fabricated by the Langmuir-Schaefer method for controlling spontaneous cell adhesion and detachment. Both the preparation of the surface and the adhesion and detachment of cells on the surface were visualized.

Research

JoVE Journal - Bioengineering
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Protein Engineering by Yeast Surface Display

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Cited by 1 •

2024

This protocol describes the essential steps for conducting yeast surface display selection campaigns to enrich protein variants binding to an antigen of interest.

Surface Engineering of Pancreatic Islets with a Heparinized StarPEG Nanocoating

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Cited by 5 •

2018

This protocol aims to achieve surface engineering of pancreatic islets using a heparin-incorporated starPEG nanocoating via pseudo-bioorthogonal chemistry between the N-hydroxysuccinimide groups of the nanocoating and the amine groups of islet cell membrane.

Engineering Antiviral Agents via Surface Plasmon Resonance

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Cited by 3 •

2022

The present protocol describes new tools for SPR binding assays to examine CV-N binding to HA, S glycoprotein, related hybrid-type glycans, and high-mannose oligosaccharides. SPR is used to determine the KD for binding either dimeric or monomeric CV-N to these glycans.

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