Preparation of Thermoresponsive Nanostructured Surfaces for Tissue Engineering

Morito Sakuma; Yoshikazu Kumashiro; Masamichi Nakayama; Nobuyuki Tanaka; Yuji Haraguchi; Kazuo Umemura; Tatsuya Shimizu; Masayuki Yamato; Teruo Okano

doi:10.3791/53465

Journal

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Bioengineering

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Preparation of Thermoresponsive Nanostructured Surfaces for Tissue Engineering

JoVE Journal
Bioengineering

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JoVE Journal Bioengineering

Preparation of Thermoresponsive Nanostructured Surfaces for Tissue Engineering

8,288 Views

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12:22 min

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March 01, 2016

DOI:

10.3791/53465-v

DOI:

10.3791/53465-v

•

12:22 min

March 01, 2016

•

8265 Views

Morito Sakuma¹, Yoshikazu Kumashiro², Masamichi Nakayama², Nobuyuki Tanaka², Yuji Haraguchi², Kazuo Umemura¹, Tatsuya Shimizu², Masayuki Yamato², Teruo Okano²

¹Department of Physics,Tokyo University of Science ²Institute of Advanced Biomedical Engineering and Science,Tokyo Women’s Medical University

Summary

Nanoscaled sea-island surfaces composed of thermoresponsive block copolymers were fabricated by the Langmuir-Schaefer method for controlling spontaneous cell adhesion and detachment. Both the preparation of the surface and the adhesion and detachment of cells on the surface were visualized.