Intra-articular Injection
Intra-articular Injection - Related Videos
08:30
Intra-articular Shoulder Injection for Reduction Following Shoulder Dislocation
0 Views •
2023
Source: Rachel Liu, BAO, MBBCh, Emergency Medicine, Yale School of Medicine, New Haven, Connecticut, USA The anterior shoulder dislocation is one of the most common joint dislocations seen in emergency settings. In anterior shoulder dislocation, the humeral head is displaced out of the glenohumeral joint in front of the scapular glenoid, resulting in a loss of the articulation between the arm and the rest of the shoulder. This can be caused by a fall onto an abducted, extended, and externally...
08:09
Osteoarthritis Pain Model Induced by Intra-Articular Injection of Mono-Iodoacetate in Rats
0 Views •
Cited by 28 •
2020
This study describes the method of intra-articular injection of mono-iodoacetate in rats and discusses the resulting pain-related behaviors and histopathological changes, which provide references for future applications.
07:10
Micro-Computed Tomography Analysis of the Knee in Aged Dunkin-Hartley Guinea Pigs after Intra Articular Injection
0 Views •
2024
Dunkin-Hartley guinea pigs are an established animal model for osteoarthritis research. Such studies may benefit from intra-articular injections for various reasons, including investigating novel agents or treating disease. We describe a methodology for intra-articular knee injections in Guinea pigs and subsequent micro-computed tomography analysis assessing arthritis-associated knee changes.
09:06
Intra-lymph Node Injection of Biodegradable Polymer Particles
0 Views •
Cited by 45 •
2014
Lymph nodes are the immunological tissues that orchestrate immune response and are a critical target for vaccines. Biomaterials have been employed to better target lymph nodes and to control delivery of antigens or adjuvants. This paper describes a technique combining these ideas to inject biocompatible polymer particles into lymph nodes.
04:20
Intra-uterine Cancer Cell Injection: A Technique to Deliver Cancer Cells for Establishing Intra-peritoneal Ovarian Cancer Mouse Model
0 Views •
2023
In this video, we demonstrate intra-uterine injection of ovarian cancer cells in a mouse model. This orthotopic murine model helps us to non-invasively monitor tumor growth and evaluate the efficacy of new therapies for the prevention and treatment of recurrent ovarian cancer.
FAQs
Corticosteroids suppress inflammation locally, while anesthetics reduce pain. Their differing actions allow a clinician to separate symptom control from anti-inflammatory treatment, and a response to injected anesthetic can also help assess whether the targeted joint contributes to pain. This local approach may limit systemic drug exposure compared with treatment delivered throughout the body.
Accurate needle placement determines whether the therapeutic fluid reaches the intended synovial joint space. Ultrasound or fluoroscopy can provide imaging guidance when direct localization is needed. This matters because misplaced delivery may fail to address the painful joint, whereas careful positioning supports targeted treatment and assessment.
The injected agent can provide information as well as symptom relief. An anesthetic may reduce pain and help clinicians assess the involved joint, while a corticosteroid may suppress local inflammation. Using these effects together helps distinguish the joint’s contribution to symptoms and supports a more targeted clinical approach.
Infection prevention, bleeding risk, and accurate placement are central safety considerations. Preparing the skin with aseptic technique helps address contamination concerns, while careful needle advancement and appropriate localization support correct delivery. These precautions are important because the procedure enters a joint space and depends on placing the agent where it is intended to act.
Ultrasound or fluoroscopy may be used when imaging guidance can help the clinician identify or access the joint space. The clinician still prepares the skin aseptically and advances the needle into the cavity, but imaging can support localization. This is particularly relevant when accurate placement is important for targeted assessment or treatment.
Intra-articular injections are used in conditions such as osteoarthritis and inflammatory arthritis. Depending on the injected formulation, the procedure may reduce pain, suppress inflammation, support joint function, or guide diagnosis. Because the agent acts locally, treatment can focus on the affected joint while potentially reducing systemic drug exposure.