Acoustic Vaporization

Acoustic vaporization is the ultrasound-triggered conversion of a liquid into a vapor, a process studied in medicine for activating phase-change droplets within the body. Focused acoustic waves deliver pressure that lowers the effective vaporization threshold of superheated droplets, causing materials such as liquid perfluorocarbons to expand rapidly into gas bubbles. These bubbles can enhance ultrasound imaging, alter local mechanical forces, or support targeted drug delivery and minimally invasive therapies. Because vaporization depends on acoustic pressure, droplet composition, temperature, and exposure conditions, the technique offers controllable activation while motivating research into treatment precision, safety, and theranostic applications.

Acoustic Vaporization - Related Videos

Research

JoVE Journal - Engineering

Synthesis of Phase-shift Nanoemulsions with Narrow Size Distributions for Acoustic Droplet Vaporization and Bubble-enhanced Ultrasound-mediated Ablation

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Cited by 18 •

2012

Phase-shift nanoemulsions (PSNE) can be vaporized using high intensity focused ultrasound to enhance localized heating and improve thermal ablation in tumors. In this report, the preparation of stable PSNE with a narrow size distribution is described. Furthermore, the impact of vaporized PSNE on ultrasound-mediated ablation is demonstrated in tissue-mimicking phantoms.

Formulation and Acoustic Modulation of Optically Vaporized Perfluorocarbon Nanodroplets

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Cited by 5 •

2021

Optically activated perfluorocarbon nanodroplets show promise in imaging applications outside of the vascular system. This article will demonstrate how to synthesize these particles, crosslink polyacrylamide phantoms, and modulate the droplets acoustically to enhance their signal.

Education

JoVE Core - Biology

Vaporization

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2019

The physical form of a substance changes by changing its temperature. For example, raising the temperature of a liquid causes the liquid to vaporize (convert into vapor). The process is called vaporization—a surface phenomenon. For vaporization to occur, kinetic energy must be greater than the intermolecular forces that keep molecules bonded. The amount of energy needed to vaporize a quantity of liquid at a given pressure and a constant temperature is called the heat of vaporization. When...

Vapor Pressure

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2020

When a liquid vaporizes in a closed container, gas molecules cannot escape. As these gas phase molecules move randomly about, they will occasionally collide with the surface of the condensed phase, and in some cases, these collisions will result in the molecules re-entering the condensed phase. The change from the gas phase to the liquid is called condensation. When the rate of condensation becomes equal to the rate of vaporization, neither the amount of the liquid nor the amount of the vapor...

Fabrication, Operation and Flow Visualization in Surface-acoustic-wave-driven Acoustic-counterflow Microfluidics

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Cited by 4 •

2013

In this video we first describe fabrication and operation procedures of a surface acoustic wave (SAW) acoustic counterflow device. We then demonstrate an experimental setup that allows for both qualitative flow visualization and quantitative analysis of complex flows within the SAW pumping device.

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