Blood Gas Measurement

Blood gas measurement is a laboratory and point-of-care method for assessing acid–base balance, oxygenation, and ventilation from a blood sample, making it important in diagnosing and monitoring critical illness. An analyzer uses electrochemical sensors to measure hydrogen-ion activity, dissolved oxygen, and carbon dioxide tension; it then reports values such as pH, PaO2, and PaCO2, with bicarbonate commonly derived from measured variables. Clinicians use arterial or venous results to evaluate respiratory failure, metabolic disturbances, shock, and responses to treatment, while trends can guide oxygen therapy, ventilation, and other urgent interventions.

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JoVE Science Education - Engineering

Noninvasive Blood Pressure Measurement Techniques

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2023

Source: Hamna J. Qureshi and Craig J. Goergen, Weldon School of Biomedical Engineering, Purdue University, West Lafayette, Indiana Here we will highlight the key similarities and differences of noninvasive blood pressure measurement techniques between humans and rodents and examine the engineering principles that govern blood pressure. The principles that govern current cuff technology to acquire systolic and diastolic pressures will also be discussed. Commercially available cuffs that connect...

Gas Absorber

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2023

Source: Michael G. Benton and Kerry M. Dooley, Department of Chemical Engineering, Louisiana State University, Baton Rouge, LA Gas absorbers are used to remove contaminants from gas streams. Multiple designs are used to accomplish this objective1. A packed bed column uses gas and liquid streams running counter to each other in a column packed with loose packing materials, such as ceramics, metals, and plastics, or structured packing1. The packed bed uses surface area created by the packing to...

Gas Exchange and Transport

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2019

Gas exchange, the intake of molecular oxygen (O2) from the environment and the outflow of carbon dioxide (CO2) into the environment, is necessary for cellular function. Gas exchange during respiration occurs largely via the movement of gas molecules along pressure gradients. Gas travels from areas of higher partial pressure to areas of lower partial pressure. In mammals, gas exchange occurs in the alveoli of the lungs, which are adjacent to capillaries and share a membrane with them. When the...

Ideal Gas Law

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2023

Source: Laboratory of Dr. Andreas Züttel - Swiss Federal Laboratories for Materials Science and Technology The ideal gas law describes the behavior of most common gases at near-ambient conditions and the tendency of all chemical matter in the dilute limit. It is a fundamental relationship between three measurable macroscopic system variables (pressure, temperature, and volume) and the number of molecules of gas in the system, and is therefore an essential link between the microscopic and the...

Ideal Gas Law - Concepts

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2020

Derivation of the Ideal Gas Law Gases are a fundamental state of matter. A gas is a collection of molecules that have a significant distance between their molecules. Due to this distance, colorless gases are invisible to the human eye and are studied using four measurable parameters: pressure (P), volume (V), number of moles (n), and temperature (T). The ideal gas law is a mathematical equation that relates all of these parameters. It is a combination of several different laws that describe the...

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