Equine Enteric Glia
Equine Enteric Glia - Related Videos
10:34
An In-vitro Preparation of Isolated Enteric Neurons and Glia from the Myenteric Plexus of the Adult Mouse
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Cited by 68 •
2013
We demonstrate a cell culture protocol for the direct study of neuronal and glial components of the enteric nervous system. A neuron/glia mixed culture on coverslips is prepared from the myenteric plexus of adult mouse providing the ability to examine individual neuron and glia function by electrophysiology, immunohistochemical, etc.
08:07
Equine Enteric Glial Culture and Application to the Study of a Neural Inflammatory Mechanism in Equine Colic
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2024
Enteric glia are becoming increasingly recognized for their roles in intestinal homeostasis and disease processes, including postoperative complications. Equine patients recovering from emergency exploratory laparotomy suffer from a high risk of inflammatory postoperative conditions, highlighting the importance of establishing repeatable equine enteric glial primary cell culture for study.
04:14
Calcium Imaging of Enteric Neuron and Glia Activities in a Mouse Colonic Myenteric Plexus
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2025
Source: Fried, D. E., Gulbransen, B. D. In Situ Ca2+ Imaging of the Enteric Nervous System. J. Vis. Exp. (2015)This video demonstrates calcium imaging to visualize and analyze the activity of enteric neurons and glia in mouse Colonic Myenteric plexus preparations.
11:26
In Situ Ca2+ Imaging of the Enteric Nervous System
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Cited by 24 •
2015
The enteric nervous system (ENS) is a network of neurons and glia located in the gut wall that controls intestinal reflexes. This protocol describes methods for recording the activity of enteric neurons and glia in live preparations of ENS using Ca2+ imaging.
09:41
Surgical Closure of Equine Abdomen, Prevention, and Management of Incisional Complications
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Cited by 3 •
2024
This paper describes a method of abdominal wall closure using tension and apposition sutures in horses undergoing ventral midline laparotomies. It also describes methods for prevention and management of postoperative incisional complications, such as bandaging, negative pressure therapy, and in case of wound breakdown, the application of retention sutures.
FAQs
Their activity is understood through interactions with enteric neurons, epithelial cells, and immune components. These relationships allow glial responses to reflect changes in gut activity or tissue stress while influencing neural function and intestinal homeostasis. Examining these cellular connections helps explain how nervous, epithelial, and immune signals may converge in the equine gastrointestinal tract.
Structural and metabolic support provide two complementary ways to understand glial influence on the enteric nervous system. Structural support helps maintain relationships among cells, whereas metabolic support contributes to the conditions required for nerve function. Considering both roles can clarify how disturbances in glial support might affect intestinal regulation without focusing only on neuronal activity.
Signals associated with tissue stress may change how these cells interact with neural, epithelial, and immune components. Because those interactions relate to motility, barrier integrity, and inflammation, stress-related glial responses could influence several aspects of intestinal homeostasis at once. This makes glial behavior relevant when investigating gastrointestinal dysfunction rather than treating each pathway as isolated.
Studies should examine glial relationships with enteric neurons, intestinal epithelial cells, and immune components, while also considering signals linked to gut activity and tissue stress. The resulting framework connects cellular communication with motility, barrier integrity, and inflammation. Such an approach can reveal how neural, epithelial, and immune pathways jointly shape intestinal function in horses.
Research on these cells can help clarify how cellular interactions influence intestinal motility, the integrity of the epithelial barrier, and inflammatory responses. These outcomes represent connected dimensions of gut function rather than separate observations. Linking them to enteric neural regulation may improve interpretation of gastrointestinal disorders associated with altered intestinal activity in horses.
Their relevance comes from the possibility that altered glial interactions may connect neural dysfunction with changes in epithelial integrity, immune signaling, motility, or inflammation. Understanding those connections could support more precise diagnostic and therapeutic strategies for equine gastrointestinal disorders. The research is therefore useful both for explaining disease mechanisms and for identifying clinically meaningful pathways to investigate.