Posterior Cerebral Artery Infarction
Posterior Cerebral Artery Infarction - Related Videos
03:15
Measuring the Infarct Zone and Brain Edema in a Rat Brain Following Middle Cerebral Artery Occlusion
0 Views •
2025
This video demonstrates the assessment of the infarct zone and brain edema in brain slices from rats subjected to middle cerebral artery occlusion. Infarcted areas are identified using redox staining, while a blue filter and threshold function in image analysis software quantify the infarct zone and edema in the affected hemisphere.
13:50
Focal Cerebral Ischemia Model by Endovascular Suture Occlusion of the Middle Cerebral Artery in the Rat
0 Views •
Cited by 107 •
2011
Surgical induction of ischemic brain damage in the rat is a widely used model for stroke research. Here we demonstrate the induction of focal cerebral ischemia by occlusion of the middle cerebral artery. Visualization of the resulting infarct by histological staining and magnetic resonance imaging is also shown.
08:27
The Application Of Permanent Middle Cerebral Artery Ligation in the Mouse
0 Views •
Cited by 29 •
2011
Middle cerebral artery (MCA) ligation is a technique to study focal cerebral ischemia in animal models. In this method, the middle cerebral artery is exposed by craniotomy and ligated by cauterization. This method gives highly reproducible infarct volumes and increased post-operative survival rates compared to other methods available.
09:40
Mouse Model of Intraluminal MCAO: Cerebral Infarct Evaluation by Cresyl Violet Staining
0 Views •
Cited by 97 •
2012
The intraluminal middle cerebral occlusion model in mice is herein presented. The extent of cerebral infarct is evaluated by a neurologic score and cresyl violet staining, an alternative staining to TTC, offering the great advantage to test in parallel many interest markers.
08:14
Modeling Stroke in Mice: Permanent Coagulation of the Distal Middle Cerebral Artery
0 Views •
Cited by 104 •
2014
Various murine models of middle cerebral artery occlusion (MCAO) are widely used in experimental brain research. Here, we demonstrate the model of transcranial permanent distal MCAO which produces consistent cortical infarction of a size corresponding to damage imposed by the majority of human ischemic strokes.
FAQs
An infarct affecting the occipital region can produce contralateral visual field loss, while involvement of temporal regions may impair memory or visual recognition. Thalamic branch involvement can add sensory deficits. Consequently, the clinical pattern depends on which supplied territories and branches lose perfusion, so patients with the same named arterial infarction may present differently.
Sensory deficits are more likely when branches supplying the thalamus are involved, whereas occipital involvement is associated with contralateral visual field loss. Temporal-region injury may affect memory or visual recognition. This anatomical relationship helps clinicians use the combination of symptoms, rather than any isolated deficit, to infer which structures may be affected.
Once perfusion falls, neurons are deprived of oxygen and glucose, limiting the energy needed to maintain normal cellular function. Persistent energy failure progresses to cellular injury and tissue death. This mechanism links the vascular event to lasting deficits, while the final clinical outcome depends on the structures affected and the extent of injury.
Evaluation combines a focused neurological examination with brain imaging. The examination can identify contralateral visual field loss, impaired visual recognition, memory problems, or sensory changes, while imaging helps assess the suspected brain injury. Using both approaches is important because affected posterior cerebral artery branches can produce different clinical findings.
Management has two time frames: acute care and recurrence prevention. Patients who meet eligibility requirements may receive acute reperfusion treatment, whereas longer-term care addresses secondary prevention. This distinction allows clinicians to respond to the immediate ischemic event while also reducing the likelihood of another stroke.
In medicine, this condition requires clinicians to connect symptoms with anatomy, imaging, and treatment timing. Visual field loss, visual recognition problems, memory impairment, and sensory deficits can point toward different affected regions. That integrated assessment supports decisions about acute reperfusion eligibility and the need for secondary prevention to reduce recurrence.