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JoVE Journal Neuroscience
Focal Cerebral Ischemia Model by Endovascular Suture Occlusion of the Middle Cerebral Artery in the Rat
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Focal Cerebral Ischemia Model by Endovascular Suture Occlusion of the Middle Cerebral Artery in the Rat

Article DOI: 10.3791/1978
February 5th, 2011 •
1, 1, 1, 1, 1
1Department of Neurological Surgery, School of Medicine and Public Health, University of Wisconsin-Madison

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February 5th, 2011

Surgical induction of ischemic brain damage in the rat is a widely used model for stroke research. Here we demonstrate the induction of focal cerebral ischemia by occlusion of the middle cerebral artery. Visualization of the resulting infarct by histological staining and magnetic resonance imaging is also shown.

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