Simple Transverse Fracture

A simple transverse fracture is a complete bone break that runs approximately perpendicular to the bone’s long axis, usually creating two main fracture fragments without multiple splintered pieces. It commonly results when a direct blow or bending force exceeds the bone’s structural strength, producing a relatively straight fracture line that can be assessed with imaging. In medicine, recognizing this fracture pattern helps clinicians evaluate displacement, alignment, soft-tissue injury, and stability. Treatment may involve immobilization or surgical fixation, depending on the bone, fracture location, and degree of displacement. Accurate classification supports appropriate management and monitoring of bone healing.

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Research

JoVE Journal - Biology

Transverse Fracture of the Mouse Femur with Stabilizing Pin

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Cited by 3 •

2021

This protocol describes a method to perform fractures on adult mice and monitor the healing process.

Minimally Invasive Transverse Aortic Constriction in Mice

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Cited by 42 •

2017

Minimally invasive transverse aortic constriction (MTAC) conserves the essentials of regular transverse aortic constriction (TAC) while eliminating the use of a ventilator with tracheal intubation. It proves to be a highly desirable method for high-throughput studies on left ventricular overload, particularly in translational studies.

Transverse Aortic Constriction in Mice

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Cited by 263 •

2010

Transverse aortic constriction (TAC) in the mouse is a commonly used experimental model to study mechanisms underlying cardiac hypertrophy and heart failure development. Here, we describe procedures to constrict the aorta to create a reproducible degree of cardiac hypertrophy in mice.

Development of a Novel Internal Fixation Model for Rat Radial Fractures: Fracture Healing Assessment and Dorsal Root Ganglion Isolation

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2026

The study innovatively combines sutures and titanium needles for stable internal fixation in a rat radial fracture model. Fracture healing was assessed via micro-computed tomography (micro-CT), and primary dorsal root ganglion (DRG) neurons were isolated and cultured for further investigation.

Sequential In vivo Imaging of Osteogenic Stem/Progenitor Cells During Fracture Repair

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Cited by 15 •

2014

Quantitative measurement of bone progenitor function in fracture healing requires high resolution serial imaging technology. Here, protocols are provided for using intravital microscopy and osteo-lineage tracking to sequentially image and quantify the migration, proliferation and differentiation of endogenous osteogenic stem/progenitor cells in the process of repairing bone fracture.

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