Medical Diagnostic
Medical Diagnostic - Related Videos
08:19
Lensless On-chip Imaging of Cells Provides a New Tool for High-throughput Cell-Biology and Medical Diagnostics
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Cited by 24 •
2009
Lensfree on-chip imaging and characterization of cells is illustrated. This on-chip cell imaging approach provides a compact and cost-effective tool for medical diagnostics and high-throughput cell biology applications, making it especially suitable for resource poor settings.
10:21
Microfluidic Applications for Disposable Diagnostics
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Cited by 1 •
2008
In this interview, Dr. Klapperich discusses the fabrication of thermoplastic microfluidic devices and their application for development of new diagnostics.
07:42
Magnetic Levitation Coupled with Portable Imaging and Analysis for Disease Diagnostics
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Cited by 11 •
2017
We present a magnetic levitation technique coupled with automated imaging and analysis in both a smartphone-compatible device and a device with embedded imaging and processing. This is applied to measure the density distribution of cells with two demonstrated biomedical applications: sickle cell disease diagnosis and separating white and red blood cells.
16:05
Using Micro-Electro-Mechanical Systems (MEMS) to Develop Diagnostic Tools
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Cited by 1 •
2007
17:16
Registered Bioimaging of Nanomaterials for Diagnostic and Therapeutic Monitoring
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Cited by 4 •
2010
Bioimaging methods used to assess cell biodistribution of nanoparticles are applicable for therapeutic and diagnostic monitoring of nanoformulated compounds. The methods described herein are sensitive and specific when assessed by histological coregistration. The methodologies provide a translational pathway from rodent to human applications.
FAQs
X-ray-based examination uses differences in X-ray absorption to create signals that represent internal anatomy. Areas that absorb X-rays differently contribute contrasting information to a radiographic image. This physics-based interaction makes radiography useful for detecting and characterizing abnormalities or injury without requiring direct access to the body during clinical evaluation.
Magnetic resonance imaging and ultrasound rely on different physical responses. Magnetic resonance imaging uses the response of atomic nuclei to magnetic fields, whereas ultrasound uses reflected sound waves. Because their signals arise from different interactions, the techniques can provide complementary views of internal structure and function when investigating disease or injury.
Detector design, image reconstruction, and quantitative analysis influence how physical interactions become interpretable diagnostic results. Detectors capture signals, reconstruction organizes those measurements into images, and quantitative analysis extracts measurable information from them. Continued improvement in these components can increase diagnostic accuracy and expand the usefulness of physics-based methods in research.
A physics-based diagnostic workflow uses a test, measurement, or imaging method to obtain signals from a measurable interaction. Those signals are converted into images or other diagnostic information, which can be examined for abnormalities and used to characterize or monitor disease or injury. This sequence connects physical measurement with clinical interpretation.
These methods are relevant in different diagnostic situations because they obtain information through different physical interactions. Radiography uses X-ray absorption, magnetic resonance imaging examines atomic-nuclei responses to magnetic fields, and ultrasound analyzes reflected sound waves. Together with nuclear medicine, they broaden noninvasive examination across questions involving internal structure, function, disease, and injury.
Medical diagnostic methods can do more than signal that something is abnormal. They can help characterize the finding, support treatment decisions, and track how disease progresses over time. In physics-based research, improved detector design, image reconstruction, and quantitative analysis also create opportunities to study measurements systematically and extend diagnostic applications.