Neural Maturation
Neural Maturation - Related Videos
03:52
Differentiation and Maturation of Human Embryonic Stem Cells into Neural Organoids
0 Views •
2025
In this video, a stepwise protocol for Human embryonic stem cells into neural organoids is demonstrated. The method involves inducing neuronal rosette formation, followed by controlled maturation and final culturing on a hydrophobic membrane to achieve fully developed neural organoids.
01:28
Maturation of Endosomes
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2023
The early endosome containing internalized molecules matures through transformations in its location, morphology, intraluminal pH, and membrane protein composition. Together, these changes result in a more acidic late endosome that contains multiple intraluminal vesicles; therefore, the late endosome is also called a multivesicular body (MVB). Changes in location The maturing endosome moves along microtubules from the periphery of the cell towards the perinuclear region. This movement of the...
10:32
Enumeration of Neural Stem Cells Using Clonal Assays
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Cited by 5 •
2016
Neural stem cells (NSCs) refer to cells which can self-renew and differentiate into the three neural lineages. Here, we describe a protocol to determine NSC frequency in a given cell population using neurosphere formation and differentiation under clonal conditions.
03:34
Isolating Cranial Neural Folds From a Chick Embryo for a Neural Crest Cell Culture
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2025
This video illustrates a technique for isolating cranial neural folds from the midbrain region of chick embryos. It presents a detailed dissection process of the neural folds, their placement, and attachment on fibronectin-coated coverslips, followed by the observation of neural crest cell migration from the neural folds.
06:24
Differentiating Human Neural Stem Cells into Neural and Astrocyte Progenitors
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2025
This video demonstrates the method to differentiate human neural stem cells from neurospheres into neural and astrocyte progenitors using enzymatic treatment and culturing in a growth factor-rich medium, which eventually leads to maturation into specialized progenitor cells.
FAQs
Synaptic formation and pruning contribute to a changing balance between connection growth and refinement. Early formation expands opportunities for communication among neurons, whereas pruning removes some connections as the nervous system becomes more specialized. In psychological research, this distinction helps relate changing neural organization to developing perception, learning, and behavior.
Myelination is one process through which neural communication becomes more efficient. As the nervous system develops, it contributes to faster and better-coordinated information processing, alongside changes in neural connectivity. These improvements help explain why psychological abilities can become more specialized and efficient across childhood, adolescence, and adulthood.
Changes in neural connectivity alter how brain regions and systems participate in information processing. Increasingly organized connectivity can support greater specialization and coordination, which are relevant to perception, learning, emotion regulation, decision-making, and social behavior. Examining these changes also helps psychologists consider how biological development and experience interact across the lifespan.
Neural maturation provides a biological framework for interpreting differences in psychological functioning at different ages. Changes in brain structure and function can be considered alongside shifts in perception, learning, emotional regulation, decision-making, and social behavior. This approach avoids treating behavior as isolated from development and connects observable changes with nervous-system refinement.
Psychologists use the framework to examine how developing neural systems relate to changing behavior across childhood, adolescence, and adulthood. It supports research on both typical development and neurodevelopmental conditions, while helping investigators interpret age-related differences in cognition, emotion, and social functioning in relation to biological development.
Studies of neural maturation can clarify how nervous-system development contributes to increasingly efficient information processing and changing psychological abilities. They can also distinguish broad patterns of typical development from features associated with neurodevelopmental conditions. The resulting context supports more precise interpretations of behavior across different stages of the lifespan.