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A Novel Stretching Platform for Applications in Cell and Tissue Mechanobiology

Article DOI: 10.3791/51454-v • 16:46 min • June 3rd, 2014
June 3rd, 2014 •
1, 1,2, 1, 3, 1,4,5
1Centre for Interdisciplinary NanoPhysics, Department of Physics, University of Ottawa, 2University of Ottawa Heart Institue, University of Ottawa, 3Libin Cardiovascular Institute of Alberta, University of Calgary, 4Department of Biology, University of Ottawa, 5Institute for Science, Society and Policy, University of Ottawa

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We present in this article a novel stretching platform that can be used to investigate single cell responses to complex anisotropic biaxial mechanical deformation and quantify the mechanical properties of biological tissues.

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Novel Stretching Platform Cell And Tissue Mechanobiology Mechanical Forces Mechanical Properties Biological Tissues Diseases Biaxial Stretching Platform Voice Coil Motors Single Cells Flexible Substrate Strain Fields Force Load Cell Primary Tissues Deformation Cycles Clamps Inverted Microscope Transmitted Light Imaging Fluorescence Imaging
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