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Ultrasound Assessment of Endothelial-Dependent Flow-Mediated Vasodilation of the Brachial Artery in Clinical Research
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JoVE Revista Medicina
Ultrasound Assessment of Endothelial-Dependent Flow-Mediated Vasodilation of the Brachial Artery in Clinical Research

Ultrasound Assessment of Endothelial-Dependent Flow-Mediated Vasodilation of the Brachial Artery in Clinical Research

27,060 Views

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08:42 min

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October 22, 2014

DOI:

10.3791/52070-v

DOI:
10.3791/52070-v

•

08:42 min
October 22, 2014

•

2 Views
, , ,
1Department of Surgery,University of California, San Francisco, 2Department of Surgery,Veterans Affairs Medical Center, San Francisco, 3VipeRx Lab,Veterans Affairs Medical Center, San Francisco

Summary

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Endothelial dysfunction is associated with numerous disease states and is predictive of adverse cardiovascular events in humans. Flow-mediated vasodilation (FMD) is a non-invasive ultrasound method of evaluating endothelial function. Methodological choices and operator experience may affect results. A systematic approach to FMD in human studies is discussed here.

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Endothelial FunctionFlow-mediated VasodilationBrachial ArteryUltrasoundEndothelial DysfunctionAtherosclerosisCoronary Artery DiseaseVascular HealthClinical ResearchOperator Dependence

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Alley, H., Owens, C. D., Gasper, W. J., Grenon, S. M. Ultrasound Assessment of Endothelial-Dependent Flow-Mediated Vasodilation of the Brachial Artery in Clinical Research. J. Vis. Exp. (92), e52070, doi:10.3791/52070 (2014).

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