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Spinal Cord Lateral Hemisection and Asymmetric Behavioral Assessments in Adult Rats
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Spinal Cord Lateral Hemisection and Asymmetric Behavioral Assessments in Adult Rats

Article DOI: 10.3791/57126-v • 08:46 min • March 24th, 2020
March 24th, 2020 •
1,2,3, 2,6, 3, 3, 3, 3,4, 3,4, 1,5, 3
1Department of Spinal Cord Injury and Repair, Trauma and Orthopedics Institute of Chinese PLA, 960th Hospital, Joint Logistics Support Force of PLA, 2Institute of Military Cognition and Brain Sciences, Academy of Military Medical Sciences, Academy of Military Sciences, 3Spinal Cord and Brain Injury Research Group, Stark Neurosciences Research Institute, Department of Neurological Surgery and Goodman Campbell Brain and Spine, Indiana University School of Medicine, 4Program in Medical Neuroscience, Paul and Carole Stark Neurosciences Research Institute, Indiana University School of Medicine, 5Department of Orthopedics, the Third Affiliated Hospital, Shandong University, 6Beijing Computing Center, Beijing Academy of Science and Technology

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Here we describe surgical procedures to produce a reliable spinal cord lateral hemisection (HX) at the 9th thoracic level in adult rats and neurobehavioral assessments designed for detecting asymmetric deficits after such a unilateral injury.

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Spinal Cord Lateral Hemisection Brown-Sequard Syndrome Animal Model Neurological Impairments Combined Behavior Scale Asymmetrical Behavior Deficits Locomotive Deficits In-lab Deficits Hemi-section Model Surgical Procedure Behavioral Procedure Anesthetized Rat Ointment Application Corneal Drying Prevention
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