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Transplantation of Adipose Tissue-Derived Stem Cell Sheet to Reduce Leakage After Partial Colectomy in A Rat Model

Article DOI: 10.3791/57213-v • 09:58 min • August 11th, 2018
August 11th, 2018 •
1,2,3, 4, 5, 4, 1,6, 1, 5, 1,5
1Department of Clinical Sciences of Companion Animals, Faculty of Veterinary Medicine, Utrecht University, 2Department of Otorhinolaryngology, Erasmus MC University Medical Center, 3Department of Clinical Sciences and Public Health, Faculty of Veterinary Science, Mahidol University, 4Department of Surgery, Erasmus MC University Medical Center, 5Department of Orthopaedics, Erasmus MC University Medical Center, 6Hill's Pet Nutrition Inc.

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Resumen
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The preparation and transplantation of adipose tissue derived stem cell (ASC) sheets onto insufficiently sutured colorectal anastomoses in a rat model is presented. This novel application shows that ASC sheets can reduce colorectal anastomosis leakage.

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Adipose Tissue-derived Stem Cell Sheet Transplantation Leakage Reduction Partial Colectomy Rat Model Tissue Healing ASC Sheets Intra-abdominal Application Synthetic Materials Not Needed Easy To Perform Novel Therapeutic Strategy Intestinal Anastomosis Promising In Preventing Leakage Application To Other Intra-abdominal Organs Urinary Tract Dissecting Subcutaneous Abdominal Adipose Tissue Isolation Medium Digestion Process Centrifugation
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