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Oleic Acid-Injection in Pigs As a Model for Acute Respiratory Distress Syndrome
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Oleic Acid-Injection in Pigs As a Model for Acute Respiratory Distress Syndrome

Article DOI: 10.3791/57783-v • 06:06 min • October 26th, 2018
October 26th, 2018 •
1, 1, 1, 1, 1, 1, 1
1Department of Anesthesiology, University Medical Center of the Johannes Gutenberg-University

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In this article, we present a protocol to induce acute lung injury in pigs by central-venous injection of oleic acid. This is an established animal model for studying the acute respiratory distress syndrome (ARDS).

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Oleic Acid-Injection Pigs Model Acute Respiratory Distress Syndrome Pathophysiologic Changes New Treatment Options Advantage Ultrasound Guided Instrumentation Right Inguinal Ligament Femoral Vessels Seldinger's Needle Cannulate Femoral Artery Ultrasound Visualization Guidance Wire Positioning Femoral Vein Ultrasonography Continuous Aspiration 5-French Arterial Introducer Sheath Venous Catheter Three-way Stopcocks Pulmonary Artery Catheter
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