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Model of Ischemic Heart Disease and Video-Based Comparison of Cardiomyocyte Contraction Using hiPSC-Derived Cardiomyocytes

Article DOI: 10.3791/61104-v • 05:06 min • May 5th, 2020
May 5th, 2020 •
*1, *1, *1, 1, 2, 1, 1
1Department of Cardiovascular Physiology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, 2Institute of Laboratory Animals, Graduate School of Medicine, Kyoto University
* These authors contributed equally

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We present a model of ischemic heart disease using cardiomyocytes derived from human induced pluripotent stem cells, together with a method for quantitative evaluation of tissue damage caused by ischemia. This model can provide a useful platform for drug screening and further research on ischemic heart disease.

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Ischemic Heart Disease Cardiomyocytes HiPSC-derived Cardiomyocytes Human IPS Cells Personalized Drug Screening Medium Change Stem Cell Differentiation Laminin Coating Incubation IPS Maintenance Medium IPS Growth Medium
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