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Anæstesi og intubation af præadolescent museunger til kardiothoracic kirurgi
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Anæstesi og intubation af præadolescent museunger til kardiothoracic kirurgi

Article DOI: 10.3791/64004-v • 09:47 min • June 2nd, 2022
June 2nd, 2022 •
*1, 1,2, 3,4, 1,2, 1,2, *1,2
1Molecular Cardiology and Biophysics Division, Victor Chang Cardiac Research Institute, 2St Vincent’s Clinical School, University of New South Wales Sydney, 3Department of Anaesthesia, The Children’s Hospital at Westmead, 4School of Child and Adolescent Health, University of Sydney
* These authors contributed equally

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Kardiothoraciske kirurgiske modeller hos mus >7 dage gamle kræver intubation, men dette er udfordrende for præadolescent (8-14 dage gamle) musehvalpe, og der er lidt information om bedøvelsesregimer til intubation. Her præsenterer vi doseringsregimer af ketamin / xylazin / atropin i 10 dage gamle C57BL / 6J museunger, der tillader endotracheal intubation, samtidig med at dyredødeligheden minimeres.

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