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Anestesi og intubasjon av preadolescent musevalper for kardiotorakisk kirurgi

Article DOI: 10.3791/64004-v • 09:47 min • June 2nd, 2022
June 2nd, 2022 •
*1, 1,2, 3,4, 1,2, 1,2, *1,2
1Molecular Cardiology and Biophysics Division, Victor Chang Cardiac Research Institute, 2St Vincent’s Clinical School, University of New South Wales Sydney, 3Department of Anaesthesia, The Children’s Hospital at Westmead, 4School of Child and Adolescent Health, University of Sydney
* These authors contributed equally

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Kardiotorakiske kirurgiske modeller hos mus >7 dager gamle krever intubasjon, men dette er utfordrende for preadolescent (8-14 dager gamle) musevalper, og det er lite informasjon om bedøvelsesregimer for intubasjon. Her presenterer vi doseringsregimer av ketamin/xylazin/atropin hos 10 dager gamle C57BL/6J musevalper som tillater endotrakeal intubasjon, samtidig som dyredødeligheten minimeres.

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