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Exploring X Chromosomal Aberrations in Ovarian Cells by Using Fluorescence In Situ Hybridization

Article DOI: 10.3791/64734-v • 11:08 min • April 7th, 2023
April 7th, 2023 •
1, 2, 1, 1,3, 1
1Department of Obstetrics and Gynecology, Radboudumc, 2Department of Pediatrics, Radboudumc, Amalia Children’s Hospital, 3Department of Reproductive Medicine, Nij Geertgen Center for Fertility

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This article presents two methods based on fluorescence in situ hybridization to determine the X chromosomal content of ovarian cells in non-grafted and grafted ovarian cortex tissue from females with X chromosomal aberrations.

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X Chromosomal Aberrations Ovarian Cells Fluorescence In Situ Hybridization FISH Analysis Reproductive Potential Diagnostic Tool Cryopreserved Ovarian Cortex Tissue Enzymatic Digestion L15 Medium Stromal Cells Follicles
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