Terapia sonodinámica para el tratamiento del glioblastoma multiforme en un modelo de ratón utilizando un sistema portátil de ultrasonido focalizado de sobremesa
4.7K vistas
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Citado 5 veces
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09:07 min
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10 de febrero de 2023
DOI :10.3791/65114-v
10 de febrero de 2023
•4.7K vistas
Griffin Mess1,2 , Taylor Anderson1,2 , Shivani Kapoor3 , Rasika Thombre1,2 , Ruixing Liang4 , Emre Derin1 , Kelley M. Kempski-Leadingham1 , Santosh K. Yadav5 , Betty Tyler1 , Amir Manbachi1,2,4,6,7
1Department of Neurosurgery, Johns Hopkins University School of Medicine, 2Department of Biomedical Engineering, Johns Hopkins University, 3Krieger School of Arts and Sciences, Johns Hopkins University, 4Department of Electrical Engineering and Computer Science, Johns Hopkins University, 5Department of Radiology, Cancer Imaging Division, Johns Hopkins University School of Medicine, 6Department of Mechanical Engineering, Johns Hopkins University, 7Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine
Aquí, describimos un protocolo que detalla cómo realizar la terapia sonodinámica en un modelo de glioblastoma de ratón in vivo utilizando ultrasonido focalizado guiado por resonancia magnética.
Chapters in this video
0:04
Introduction
1:31
Animal Preparation for Sonodynamic Therapy (SDT)
2:42
MRI Procedures
5:42
Focused Ultrasound Treatment
7:34
Results: Reduction in Tumor Size After SDT Treatment in Animals with GBM Tumors
8:15
Conclusion
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