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Developing a Simple and Robust Hepatic Model for Pharmacological and Toxicological Applications (Video) | JoVE

A Physiologically-Relevant All-Human 2D+ Hepatic System for Drug Discovery

Article DOI: 10.3791/65992-v • 01:11 min • October 20th, 2023
October 20th, 2023 •
1, 2, 3, 4, 1, 1
1Institute of Regenerative Medicine, LifeNet Health, 2Biologics Division, LifeNet Health, 3LifeSciences Division, LifeNet Health, 4Research and Development, LifeSciences, LifeNet Health

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모든 인간 간 배양 시스템 약물 개발 1 차 인간 간세포 약리학 연구 독성 연구 체외 모델 플랫폼 표현형 안정성 실험 재현성 해동 도금 유지 보수 2 차원 배양 기술 3 차원 시스템 부착 도금성 파종 밀도 기능성 장기 배양 간세포 콜로니 간 특이적 마커 생존력 건축 무결성 알부민 수준 요소 수준 약리학적 응용 독성학적 응용분야
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