Aleksandra Sokolowska-Wedzina Department of Protein Engineering, Faculty of Biotechnology University of Wroclaw Biography Publications Institution JoVE Articles Aleksandra Sokolowska-Wedzina has not added a biography. If you are Aleksandra Sokolowska-Wedzina and would like to personalize this page please email our Author Liaison for assistance. Publications FGFR1 Clustering with Engineered Tetravalent Antibody Improves the Efficiency and Modifies the Mechanism of Receptor Internalization Molecular Oncology. 09, 2020 | Pubmed ID: 32511887 Generation of High-affinity, Internalizing Anti-FGFR2 Single-chain Variable Antibody Fragment Fused with Fc for Targeting Gastrointestinal Cancers PloS One. 2018 | Pubmed ID: 29420662 Cytotoxic Conjugates of Fibroblast Growth Factor 2 (FGF2) with Monomethyl Auristatin E for Effective Killing of Cells Expressing FGF Receptors ACS Omega. Jul, 2017 | Pubmed ID: 30023704 Design and In Vitro Evaluation of a Cytotoxic Conjugate Based on the Anti-HER2 Affibody Fused to the Fc Fragment of IgG1 International Journal of Molecular Sciences. Aug, 2017 | Pubmed ID: 28771178 Antibody-induced Dimerization of FGFR1 Promotes Receptor Endocytosis Independently of Its Kinase Activity Scientific Reports. 08, 2017 | Pubmed ID: 28769084 The Autoinhibitory Function of D1 Domain of FGFR1 Goes Beyond the Inhibition of Ligand Binding The International Journal of Biochemistry & Cell Biology. 08, 2017 | Pubmed ID: 28652212 High-Yield Site-Specific Conjugation of Fibroblast Growth Factor 1 with Monomethylauristatin E Via Cysteine Flanked by Basic Residues Bioconjugate Chemistry. 07, 2017 | Pubmed ID: 28598150 High-Affinity Internalizing Human ScFv-Fc Antibody for Targeting FGFR1-Overexpressing Lung Cancer Molecular Cancer Research : MCR. 08, 2017 | Pubmed ID: 28483948 Selection and Characterization of Single Chain Antibody Fragments Specific for Hsp90 As a Potential Cancer Targeting Molecule International Journal of Molecular Sciences. Aug, 2015 | Pubmed ID: 26307975 Efficient Production and Purification of Extracellular Domain of Human FGFR-Fc Fusion Proteins from Chinese Hamster Ovary Cells Protein Expression and Purification. Jul, 2014 | Pubmed ID: 24727156 Preparation of Site-Specific Cytotoxic Protein Conjugates via Maleimide-thiol Chemistry and Sortase A-Mediated Ligation Mateusz Adam Krzyscik1,2, Aleksandra Sokolowska-Wedzina1, Karolina Jendryczko1, Marta Pozniak1, Daria Nawrocka1, Natalia Porebska1, Malgorzata Zakrzewska1, Jacek Otlewski1, Anna Szlachcic1, Lukasz Opalinski1 1Department of Protein Engineering, Faculty of Biotechnology, University of Wroclaw, 2Department of Protein Biotechnology, Faculty of Biotechnology, University of Wroclaw JoVE 61918 Biochimie
Preparation of Site-Specific Cytotoxic Protein Conjugates via Maleimide-thiol Chemistry and Sortase A-Mediated Ligation Mateusz Adam Krzyscik1,2, Aleksandra Sokolowska-Wedzina1, Karolina Jendryczko1, Marta Pozniak1, Daria Nawrocka1, Natalia Porebska1, Malgorzata Zakrzewska1, Jacek Otlewski1, Anna Szlachcic1, Lukasz Opalinski1 1Department of Protein Engineering, Faculty of Biotechnology, University of Wroclaw, 2Department of Protein Biotechnology, Faculty of Biotechnology, University of Wroclaw JoVE 61918 Biochimie