Hydrogen Balloon Method

The hydrogen balloon method is a laboratory technique for carrying out catalytic hydrogenation by supplying hydrogen gas from a flexible balloon to a reaction mixture, typically at near-atmospheric pressure. A catalyst such as palladium, platinum, or nickel activates hydrogen at its surface, allowing hydrogen atoms to add across unsaturated bonds in compounds such as alkenes, alkynes, or carbonyl-containing substrates. This approach provides a simple alternative to pressurized hydrogen equipment and is widely used for reducing functional groups, removing protecting groups, and preparing more saturated molecules in synthetic chemistry. Careful control of the catalyst, solvent, gas contact, and flammability hazards is essential.

Hydrogen Balloon Method - Related Videos

Education

JoVE Science Education - Chemistry

Hydrogenation

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2023

Source: Vy M. Dong and Zhiwei Chen, Department of Chemistry, University of California, Irvine, CA This experiment will demonstrate the hydrogenation of chalcone as an example of an alkene hydrogenation reaction (Figure 1). In this experiment, palladium on carbon (Pd/C) will be used as a heterogeneous catalyst for the process. A balloon will be used to supply the hydrogen atmosphere. Figure 1: Diagram showing the hydrogenation of chalcone to 3-phenylpropiophenone.

Research

JoVE EoE - Bacterial Growth and Techniques

A Sensitive Visual Method for the Detection of Hydrogen Sulfide-Producing Bacteria

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2025

Source: Zhu, W., & Chu, W. Sensitive Visual Method for the Detection of Hydrogen Sulfide Producing Bacteria. J. Vis. Exp. (2022)This video demonstrates a sensitive visual method for the rapid detection of hydrogen sulfide–producing bacteria. A color change from yellow to black indicates bacterial activity through the formation of bismuth sulfide.

Inducing Brain Death in a Mouse Model Using a Balloon Catheter

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2025

This video demonstrates the procedure for inducing brain death in a mouse model by increasing controlled intracranial pressure through a balloon catheter, mimicking natural brain death.

Catalytic Reactor: Hydrogenation of Ethylene

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2023

Source: Kerry M. Dooley and Michael G. Benton, Department of Chemical Engineering, Louisiana State University, Baton Rouge, LA The hydrogenation of ethylene (C2H4) to ethane (C2H6) has often been studied as a model reduction reaction in characterizing new metal catalysts.1-2 While supported nickel is not the most active metal catalyst for this reaction, it is active enough that reaction can take place at < 200°C. The reaction typically involves adsorbed, dissociated hydrogen (H2) reacting...

A Rat Carotid Balloon Injury Model to Test Anti-vascular Remodeling Therapeutics

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Cited by 8 •

2016

The rat carotid balloon injury model described below allows researchers to evaluate drugs or therapeutics that negate injury-induced arterial hyperplasia. Detailed pre-surgical preparation, surgical procedure, and post-surgical cares of the animal are described.

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