Lumbar Sacral Spine

The lumbar sacral spine, often called the lumbosacral spine, is the lower segment of the vertebral column formed by the five lumbar vertebrae, the sacrum, and their interconnecting joints; it supports the trunk and transfers body weight to the pelvis. Its vertebrae, intervertebral discs, ligaments, and facet joints permit controlled flexion, extension, and rotation while protecting the neural structures that serve the lower body. In clinical practice, assessment of this region helps identify mechanical back pain, disc herniation, spinal stenosis, fractures, and nerve compression. Physical examination and imaging guide diagnosis, treatment planning, and monitoring of recovery.

Lumbar Sacral Spine - Related Videos

Research

JoVE EoE - Rodent Models

Surgical Induction of Lumbar Spine Instability in Mouse Model: A Surgical Procedure for the Resection of the Lumbar Spinous Processes and Connected Ligaments in Murine Model

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2025

In this video, we describe the surgical procedure to induce lumbar spine instability in a mouse model by resecting the Lumbar L3 to L5 spinous process along with supraspinous and interspinous ligaments.

Intrathecal Placement of Lumbar Drain: A Technique to Withdraw Cerebrospinal Fluid from the Lumbar Spine in Porcine Model

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2025

This video describes the technique of intrathecal placement of a lumbar drain in a porcine ischemic model, which helps in draining the cerebrospinal fluid to a drainage system. The cerebrospinal fluid pressure is monitored by the drainage system, and fluid is drained to maintain a constant cerebrospinal fluid pressure.

A Mouse Model of Lumbar Spine Instability

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Cited by 14 •

2021

We developed a lumbar intervertebral disc degeneration mouse model by resection of L3–L5 spinous processes along with supra- and inter-spinous ligaments and detachment of paraspinous muscles.

An Anesthesia, Surgery, and Harvest Method for the Evaluation of Transpedicular Screws Using an In Vivo Porcine Lumbar Spine Model

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2017

Here, we introduce a method to evaluate transpedicular screws by using an in vivo porcine lumbar spine model.

Harvesting DRG from Rat Spine: A Procedure to Extract Dorsal Root Ganglion from the Spine of a Rat Model

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2023

In this video, we demonstrate the extraction of dorsal root ganglion or DRG from a harvested rat spine for downstream applications.

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