Cardiac Thrombus Evaluation
Cardiac Thrombus Evaluation - Related Videos
06:29
Cardiac Magnetic Resonance for the Evaluation of Suspected Cardiac Thrombus: Conventional and Emerging Techniques
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Cited by 6 •
2019
The goal of this article is to describe how cardiac magnetic resonance can be used for the evaluation and diagnosis of a suspected cardiac thrombus. The method presented will describe data acquisition as well as the pre-procedure and post-procedure protocol.
08:50
Thrombus Profiling Assay: A Microfluidics-Based Platform for Comprehensively Characterizing Biomechanical Thrombogenesis
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2026
This work describes a microfluidic assay that uses shear stress to trigger thrombus formation in blood and characterizes the thrombus by multiple dimensions of readout. The assay can measure the prothrombotic tendency of blood samples, and is thus useful in disease diagnosis, drug discovery, as well as basic mechanistic studies related to thrombosis.
09:01
Intravital Microscopy and Thrombus Induction in the Earlobe of a Hairless Mouse
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Cited by 4 •
2017
The ear model of the hairless SKH1-Hrhr mouse enables intravital fluorescence microscopy of microcirculation and phototoxic thrombus induction without prior surgical preparation in the examined microvascular bed. Therefore, the ear of the hairless mouse is an excellent in vivo model to study the complex interactions during microvascular thrombus formation, thrombus evolution, and thrombolysis.
05:54
Intravital Fluorescence Microscopy to Study Microvascular Thrombus Formation
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2025
This video demonstrates the intravital fluorescence microscopy technique to study thrombus formation in a mouse model. The mouse is injected with a fluorophore-labeled polysaccharide to monitor blood circulation. Upon illumination with a high-intensity light, the phototoxic induction of an injury in the microvasculature of the ear leads to the formation of a thrombus, which is confirmed by visualizing the obstruction in the blood flow.
02:05
Visualization of a Cerebral Thrombus in a Mouse Using Micro-Computed Tomography Imaging
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2025
Source: Kim, D., et. al. Combined Near-infrared Fluorescent Imaging and Micro-computed Tomography for Directly Visualizing Cerebral Thromboemboli. J. Vis. Exp. (2016)This video demonstrates visualization of cerebral thrombus in mice using micro-computed tomography (micro-CT) imaging. A cerebral thrombus mouse model is injected with fibrin-targeted gold nanoparticles acting as a contrasting agent. The mouse is placed on the bed of a micro-CT machine, and images are acquired from multiple angles.
FAQs
Interpretation depends on the mass’s position, mobility, morphology, contrast filling, and tissue characteristics rather than on a single visual feature. A lesion attached in a particular cardiac location or moving with blood flow may carry different implications from a fixed structure. Assessing these attributes systematically supports more reliable characterization.
Transthoracic echocardiography, transesophageal echocardiography, cardiac CT, and cardiac MRI contribute different imaging views of a suspected intracardiac mass. The evaluation uses these modalities to examine anatomy, motion, contrast behavior, and tissue properties. Considering the findings together can help separate thrombus from tumor, vegetation, or normal anatomy.
Thrombus, tumor, vegetation, and normal anatomical structures can appear as masses but lead to different clinical interpretations. Correct characterization therefore affects risk assessment and the next management discussion. In particular, identifying a finding as compatible with thrombus can support decisions about anticoagulation and whether imaging follow-up is needed.
The process begins with clinical findings that raise concern, followed by targeted cardiac imaging. Echocardiography, cardiac CT, or cardiac MRI can then be used to examine the suspected mass’s location, mobility, morphology, contrast filling, and tissue characteristics. The resulting characterization guides assessment rather than relying on a single feature.
Location and mobility help describe how the mass relates to cardiac structures, while morphology, contrast filling, and tissue characteristics add information about its nature. Together, these observations support clinical decisions such as anticoagulation, procedural planning, and selection of follow-up imaging. Their value lies in connecting image characterization with a specific management question.
Follow-up imaging can show whether a cardiac thrombus resolves or persists over time. That comparison gives clinicians an objective way to reassess the previously characterized finding and its ongoing significance. It also complements management decisions by showing whether the imaging appearance has changed after the initial evaluation rather than treating the first study as final.