Contrast Enhanced Ct

Contrast-enhanced computed tomography (CT) is an imaging technique that combines cross-sectional X-ray imaging with a contrast agent to improve the visibility of blood vessels, organs, and abnormal tissue. During the scan, an iodinated contrast medium is commonly administered intravenously, where its high X-ray attenuation increases differences between tissues and produces enhancement that varies with circulation and scan timing. Contrast-enhanced CT supports the evaluation of tumors, inflammation, infection, vascular disease, trauma, and organ perfusion, helping clinicians characterize abnormalities and guide diagnosis and treatment. Protocols can be adjusted to capture arterial, venous, or delayed phases while considering renal function and potential contrast reactions.

Contrast Enhanced Ct - Related Videos

Research

JoVE EoE - Neuroimaging

Contrast-Enhanced Micro-CT Imaging of Cerebral Cavernous Malformation Lesions in a Mouse Brain

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2025

Source: Choi, J. P. et al. Induction and Micro-CT Imaging of Cerebral Cavernous Malformations in Mouse Model. J. Vis. Exp. (2017)This video demonstrates the use of micro-CT imaging to visualize cerebral cavernous malformation (CCM) lesions in a mouse brain. It details the steps for sample preparation, imaging, and 3D image reconstruction to evaluate the density and location of CCM lesions in brain tissue.

Contrast Enhanced Vessel Imaging using MicroCT

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Cited by 17 •

2011

Contrast enhanced small animal vessel imaging by microCT is a rapid, cost-effective and high-throughput technique for serial in situ examination for tumor development, for analyzing the network of blood vessels that nourish them, and for following the response of tumors to preclinical therapeutic intervention(s).

In vivo Imaging of Optic Nerve Fiber Integrity by Contrast-Enhanced MRI in Mice

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Cited by 7 •

2014

This video illustrates a method, using a clinical 3 T scanner, for contrast-enhanced MR imaging of the naïve mouse visual projection and for repetitive and longitudinal in vivo studies of optic nerve degeneration associated with acute optic nerve crush injury and chronic optic nerve degeneration in knock-out mice (p50KO).

Dynamic Contrast Enhanced Magnetic Resonance Imaging of an Orthotopic Pancreatic Cancer Mouse Model

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Cited by 9 •

2015

The goal of this protocol is to apply dynamic contrast enhanced magnetic resonance imaging (DCE-MRI) for orthotopic pancreatic tumor xenografts in mice. DCE-MRI is a non-invasive method to analyze microvasculature in a target tissue, and useful to assess vascular response in a tumor following a novel therapy.

Research

JoVE Journal - Biology
Free Sample

Phase Contrast and Differential Interference Contrast (DIC) Microscopy

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Cited by 26 •

2008

This protocol highlights the principles and practical applications of Phase and Differential Interference Contrast (DIC)...

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