Expanded Disability Status

Expanded Disability Status, commonly assessed with the Expanded Disability Status Scale (EDSS), is a clinical framework for describing neurological disability, particularly in people with multiple sclerosis. A clinician combines findings from functional systems, such as vision, motor function, coordination, sensation, and bladder or bowel control, with the patient’s ability to walk and perform daily activities to assign a score from 0, indicating normal function, to 10, indicating death from multiple sclerosis. The scale supports disease monitoring, treatment evaluation, clinical-trial outcome measurement, and communication about changes in neurological function, although it emphasizes mobility more than some other aspects of disability.

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Intellectual disability (ID) is a neurodevelopmental condition characterized by deficits in intellectual and adaptive functioning that manifest during the developmental period. This condition encompasses challenges in reasoning, memory, problem-solving, and learning, accompanied by impairments in everyday life skills, such as communication, self-care, and social interactions. Intellectual disability affects approximately 1% of the population in the United States, impacting an estimated 5...

Learning Disabilities

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Learning disabilities are cognitive disorders caused by neurological impairments that affect cognitive functions like language and reading, without indicating overall intellectual or developmental challenges. These disabilities differ from global intellectual or developmental disabilities as they are limited to distinct cognitive functions. Common learning disabilities include dysgraphia, dyslexia, and dyscalculia, each of which impacts unique aspects of learning. Dyslexia Dyslexia is a...

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JoVE Journal - Behavior

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Objective and easy measurement of sensory processing is extremely difficult in nonverbal or vulnerable pediatric patients. We developed a new methodology to quantitatively assess infants and children's cortical processing of light touch, speech sounds, and the multisensory processing of the 2 stimuli, without requiring active subject participation or causing discomfort in vulnerable patients.

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An optimized testing protocol is presented in this paper for the Rotarod performance test, used for measuring progressive neurological disability in TMEV-infected mice.

Mental Status Examination

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2023

Source: Carmen Black, Matthew Goldenberg, and Jaideep Talwalkar; Yale School of Medicine The mental status exam is a clinical evaluation of emotional, perceptual, and cognitive functioning that spans both the fields of psychiatry and neurology. Developing skill in the psychiatric portions of the examination are important to describe salient aspects of the patient's mental state that may be observed during routine history and/or physical exam. Proficiency in the cognitive portions of this...

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