Dorsal Cutaneous Nerves

Dorsal cutaneous nerves are peripheral sensory branches that supply the skin of the back, providing an essential link between surface tissues and the nervous system. Typically arising from the dorsal rami of spinal nerves, they carry signals generated by cutaneous mechanoreceptors, thermoreceptors, and nociceptors through spinal pathways to the central nervous system, where touch, temperature, and pain are processed. In neuroscience, studying these nerves helps clarify segmental sensory organization, somatosensory mapping, and the neural basis of back pain. Their anatomy also informs clinical assessment, nerve-block procedures, and research on peripheral nerve injury and sensory recovery.

Dorsal Cutaneous Nerves - Related Videos

Research

JoVE Journal - Medicine

Cutaneous Surgical Denervation: A Method for Testing the Requirement for Nerves in Mouse Models of Skin Disease

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Cited by 9 •

2016

This article includes detailed protocols for genetic labeling of mouse skin, surgical denervation, skin biopsy and visualizing labeled epithelia by whole-mount β-galactosidase staining. These methods can be used to test the requirement for nerves in mouse models of normal and pathological skin.

Cutaneous Leishmaniasis in the Dorsal Skin of Hamsters: a Useful Model for the Screening of Antileishmanial Drugs

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Cited by 40 •

2012

Optimization of the experimental hamster model for cutaneous leishmaniasis by intradermal injection of Leishmania promastigotes at the dorsal skin. This approach is useful during inoculation, follow-up, characterization of lesions, application of treatments and obtaining of clinical samples. Locomotion, search for food and water, play and social activities are preserved.

Frozen Skin Tissue Block Preparation: A Protocol to Preserve Cutaneous Melanoma Samples from Murine Dorsal Skin

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2023

This video describes the detailed protocol for isolating melanoma-containing murine dorsal skin, followed by cryo-embedding to prepare a frozen skin tissue block. The cryo-embedded tissue block can be sectioned and microscopically examined to study melanoma progression.

Research

JoVE Journal - Medicine
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Dual-mode Imaging of Cutaneous Tissue Oxygenation and Vascular Function

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Cited by 16 •

2010

A dual-mode imaging system was developed for non-contact assessment of cutaneous tissue oxygenation and vascular function.

Testing Sensory Nerve Function in a Surgically Denervated Mouse Model

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2025

This video demonstrates testing sensory nerve function in a mouse model by surgically denervating one side and leaving the other as a control. The response to mechanical stimulation confirms the role of sensory nerves.

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