Olfactory Behaviors

Olfactory behaviors are actions shaped by the detection and interpretation of odors, including finding food, avoiding danger, recognizing social cues, and selecting environments. Odor molecules bind receptors in olfactory sensory neurons, which convert chemical signals into patterns of activity transmitted to the olfactory bulb and then to brain circuits involved in motivation, memory, emotion, and decision-making. In neuroscience, studying these behaviors links sensory coding to navigation, learning, and adaptive choice across species. Behavioral assays that measure attraction, avoidance, investigation, or odor-guided learning help researchers examine neural circuit function and understand how sensory information influences health and behavior.

Olfactory Behaviors - Related Videos

Research

JoVE Journal - Biology

Olfactory Behavioral Testing in the Adult Mouse

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Cited by 68 •

2009

Fundamental, yet unique properties of the rodent olfactory system have led to its increasing study among biologists. A relatively simple assessment of its function is then also needed. Here we describe sensitive tests for the characterization of mouse olfactory sensitivity and preference.

Olfactory Behaviors Assayed by Computer Tracking Of Drosophila in a Four-quadrant Olfactometer

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Cited by 4 •

2016

We describe here a behavioral setup and data analysis method for assaying olfactory responses of up to 100 vinegar flies (Drosophila melanogaster). This system may be used with single or multiple olfactory stimuli, and adaptable for optogenetic activation or silencing of neuronal subsets.

Research

JoVE Journal - Behavior
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Constructing an Olfactometer for Rodent Olfactory Behavior Studies

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Cited by 1 •

2025

This protocol describes the construction of an olfactometer for go/no-go olfactory behavior experiments. Step-by-step instructions, along with images, are provided to ensure the successful construction of the olfactometer. Information for troubleshooting issues encountered during the process is also included.

Navigational Behavior of Drosophila Larvae in Response to Optogenetic Stimulation of Olfactory Sensory Neurons

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2025

This video demonstrates a study of the navigational behavior of Drosophila larvae in response to optogenetic stimulation of olfactory sensory neurons (ORNs). Transgenic Drosophila larvae expressing light-sensitive ion channels in the ORNs are placed on agarose within a behavior arena. Optogenetic stimulation with light opens the channels, causing a cation influx that triggers the transmission of the signal to the brain, and the navigation behavior is recorded.

Simple and Computer-assisted Olfactory Testing for Mice

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Cited by 9 •

2015

We present a simple and unbiased olfactory test in mice. With this protocol olfactory discrimination, preference, avoidance and sensitivity to a novel odor as compared to water can be assessed in single behavioral sessions. This method is indicated for a single experimenter and analysis is based on computer-assisted video processing.

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