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The Tail Suspension Test
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The Tail Suspension Test

The Tail Suspension Test

77,716 Views

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10:17 min

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January 28, 2012

DOI:

10.3791/3769-v

DOI:
10.3791/3769-v

•

10:17 min
January 28, 2012

•

102 Views
, , , , ,
1Department of Psychiatry,University of Maryland School of Medicine, 2Tulane University School of Medicine, 3The Program in Neuroscience,University of Maryland , 4Department of Pharmacology and Experimental Therapeutics,University of Maryland School of Medicine

Summary

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The tail-suspension test is validated as an experimental procedure to assess antidepressant efficacy of drug treatments in mice. Mice are suspended by their tails for six minutes and escape-related behaviors are assessed. We describe procedures used in conducting the tail suspension test.

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Can, A., Dao, D. T., Terrillion, C. E., Piantadosi, S. C., Bhat, S., Gould, T. D. The Tail Suspension Test. J. Vis. Exp. (59), e3769, doi:10.3791/3769 (2012).

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