JoVE Journal
Medicine
Medicine
Un abonnement à JoVE est nécessaire pour afficher ce contenu.
Chapitres
résumé
These studies report on reversible attachment of adenoviral gene vectors to coatless metal surfaces of stents and model mesh disks. Sustained release of transduction-competent viral particles contingent upon hydrolysis of cross-linkers used for vector immobilization results in a durable site-specific transgene expression in vascular cells and in stented arteries.