Hashin Failure Criteria

Hashin failure criteria are a set of failure theories used to predict damage initiation in anisotropic fiber-reinforced composite materials under multiaxial loading. They evaluate stresses in material directions against strength parameters through separate interaction equations for fiber tension, fiber compression, matrix tension, and matrix compression, allowing the criteria to distinguish likely failure modes rather than treating the composite as isotropic. Engineers apply these criteria in finite element analysis and composite structural design to identify critical load cases, assess safety margins, and guide material selection or laminate optimization. When combined with damage-evolution models, they can also support simulations of progressive failure.

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Education

JoVE Core - Statistics

Criteria for Causality: Bradford Hill Criteria - II

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2025

The Bradford Hill criteria serve as guidelines for establishing causative links in epidemiological research. Beyond Strength, Consistency, Specificity, and Temporality, key criteria also include Biological Gradient, Plausibility, Coherence, Experiment, and Analogy. These principles assist scientists in assessing the likelihood of causation in complex biological contexts. Below is a summary of these concepts: Biological Gradient: Also known as the dose-response relationship, this criterion...

Criteria for Causality: Bradford Hill Criteria - I

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2025

The Bradford Hill criteria are a group of principles that provide a framework to determine a causal relationship between a specific factor and a disease. There are nine criteria that are pivotal in assessing causality in epidemiological studies. Here's a closer look at Strength, Consistency, Specificity, and Temporality criteria with definitions and examples: Strength: This criterion refers to the size of the association between the factor and the outcome. A strong association suggests a...

Yield Criteria for Ductile Materials under Plane Stress

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2024

In designing structural elements and machine parts using ductile materials, it is crucial to ensure that these components withstand applied stresses without yielding. Yielding is initially determined through a tensile test, which evaluates the material's response to uniaxial stress. However, tensile stress is insufficient when components face biaxial or plane stress conditions This condition requires advanced criteria to predict failure. The Maximum Shearing Stress Criterion, also known as the...

Criteria for Aromaticity and the Hückel 4n + 2 Rule

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2023

Like benzene, cyclobutadiene and cyclooctatetraene are cyclic compounds with alternate single and double bonds. However, their chemical behavior differs from benzene, as they are unstable and not aromatic. So, what are the structural characteristics of unsaturated compounds categorized as aromatic? For the first time, Eric Hückel, a German chemical physicist, derived a set of structural features for a compound to be classified as aromatic. This is now known as Hückel’s rule or the 4n + 2 rule.

Research

JoVE Journal - Medicine

Gene Transfer for Ischemic Heart Failure in a Preclinical Model

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Cited by 21 •

2011

A method of gene transfer for the treatment of ischemic heart failure is described using a swine model of myocardial infarction. Our simple and reproducible method enables us to readily evaluate the efficacy of various gene transfers with a very simple and reproducible way.

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