Physiological Response

Physiological response is the measurable change in an organism’s function triggered by an internal or external stimulus, providing insight into how biological systems adapt to changing conditions. It arises through coordinated neural, hormonal, cardiovascular, respiratory, and metabolic processes that regulate variables such as heart rate, blood pressure, temperature, and oxygen use. In engineering, researchers measure these responses with biosensors, wearable devices, and biomechanical systems to evaluate human performance, design safer products, and develop responsive medical technologies. Physiological-response data also support rehabilitation, ergonomics, environmental monitoring, and human-machine interaction by linking biological function to engineered systems and operating conditions.

Physiological Response - Related Videos

Research

JoVE EoE - Neurophysiology

Detecting Physiological Responses from Sensory Neurons in Drosophila

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2025

This video demonstrates a method for detecting sensory neuron responses in Drosophila using ligand binding and fluorescence imaging. Ligands bind to neuron receptors, causing calcium influx. The calcium binds to indicator complexes, leading to fluorescence emission, which confirms the neuronal response to the ligand.

Measurements of Physiological Stress Responses in C. Elegans

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Cited by 44 •

2020

Here, we characterize cellular proteotoxic stress responses in the nematode C. elegans by measuring the activation of fluorescent transcriptional reporters and assaying sensitivity to physiological stress.

Measuring Physiological Responses of Drosophila Sensory Neurons to Lipid Pheromones Using Live Calcium Imaging

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Cited by 4 •

2016

The forelegs and proboscis of Drosophila contain a rich repertoire of gustatory sensory neurons. Here, we present a method using calcium imaging to measure physiological responses from sensory neurons in the foreleg and proboscis of live flies upon exogenous application of a gustatory pheromone.

A Community-based Stress Management Program: Using Wearable Devices to Assess Whole Body Physiological Responses in Non-laboratory Settings

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Cited by 1 •

2018

Stress is an unavoidable and persistent component of life and holistic approaches for its management are being considered. A standardized methodology was created to demonstrate the feasibility of a breath-based stress management protocol that can be used with commercially available portable technology.

Education

JoVE Lab Manual - Biology

Physiology of the Circulatory System - Concepts

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2019

Homeostasis Conditions in the external environment of an organism can change rapidly and drastically. To survive, organisms must maintain a fairly constant internal environment, which involves continuous regulation of temperature, pH, and other factors. This balanced state is known as homeostasis, which describes the processes by which organisms maintain their optimal internal conditions. To maintain homeostasis, organisms have developed structures with distinct functions. Physiology is the...

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