Successive Differentiation

Successive differentiation is the process of differentiating a function repeatedly to obtain its second, third, and higher-order derivatives. Each step applies standard rules such as the product, quotient, and chain rules to the derivative produced in the preceding step, provided the required derivatives exist; the resulting nth derivative describes how lower-order rates of change themselves vary. In mathematics, these derivatives support Taylor and Maclaurin series, where derivative values generate local polynomial approximations, and help analyze curvature, extrema, and the behavior of solutions to differential equations. The method also provides a foundation for studying smoothness and modeling changing quantities.

Successive Differentiation - Related Videos

Education

JoVE Core - Biology

Ecological Succession

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2026

Ecological succession is influenced by the processes of facilitation, inhibition, and toleration. Facilitation occurs when early successional species create more favorable ecological conditions for subsequent species, such as enhanced nutrient, water, or light availability. In contrast, inhibition happens when early successional species create unfavorable ecological conditions for potential successive species, such as limiting resource availability. In some cases, later successional species...

Research

JoVE Journal - Behavior
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The Successive Alleys Test of Anxiety in Mice and Rats

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Cited by 49 •

2013

The plus-maze measures anxiety-like behaviour in rodents. There are two opposite closed and two opposite open arms; anxious rodents avoid the open arms. The central area is neither completely open nor closed, so time spent here is ambiguous and difficult to interpret. Here a modification of the plus-maze protocol eliminating this area is described.

Improving the Success Rate of Protein Crystallization by Random Microseed Matrix Screening

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Cited by 20 •

2013

Here we describe a general method for random microseed matrix screening. This technique is shown to significantly increase the success rate of protein crystallization screening experiments, reduce the need for optimization, and provide a reliable supply of crystals for data collection and ligand-soaking experiments.

Reduced Itraconazole Concentration and Durations Are Successful in Treating Batrachochytrium dendrobatidis Infection in Amphibians

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Cited by 18 •

2014

Batrachochytrium dendrobatidis infection in amphibians can be eliminated using a reduced concentration (0.0025%) and shorter duration (five minute baths for six days) of itraconazole than is generally used. Less mortality and fewer negative side effects were observed using this modified treatment protocol.

Setting a Successful Sorting for Extracellular Vesicle Isolation

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Cited by 2 •

2024

This protocol provides a detailed description of sorting extracellular vesicles (EVs) released by mesenchymal stromal cells. In particular, it focuses on the instrument setting and the optimization of the sorting conditions. The goal is to sort extracellular vesicles while preserving their characteristics.

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