Human Brain
Human Brain - Related Videos
11:31
A Chromatin Assay for Human Brain Tissue
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Cited by 16 •
2008
Until recently, expression studies on human brain were limited to quantification of RNA or protein. With the chromatin immunoprecipitation techniques described in this paper, it will be possible to map histone methylation and other epigenetic regulators of gene expression in postmortem brain.
06:28
Isolation of Cerebral Capillaries from Human Brain: An Optimized Method to Extract Cerebral Capillaries from Human Brain Tissue
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2025
This video presents the isolation of cerebral capillaries from a fresh human brain tissue. The isolated capillaries can then be used to generate an ex vivo blood brain barrier model.
09:09
Dissecting the Non-human Primate Brain in Stereotaxic Space
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Cited by 14 •
2009
The non-human primate is an important translational species for our understanding of the normal processing of the brain. The anatomical organization of the primate brain can provide important insights into normal and pathological conditions in humans.
08:29
Symmetric Bihemispheric Postmortem Brain Cutting to Study Healthy and Pathological Brain Conditions in Humans
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Cited by 7 •
2016
Organized brain cutting procedures are necessary to correlate specific neuropsychiatric phenomena with definitive neuropathologic diagnoses. Brain cuttings are performed differently based on various clinico-academic contingencies. This protocol describes a symmetric bihemispheric brain cutting procedure to investigate hemispheric differences in human brain pathologies and to maximize current and future biomolecular/neuroimaging techniques.
03:46
Symmetric Bihemispheric Sectioning of the Human Postmortem Brain
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2025
The video demonstrates a step-by-step procedure for symmetrically dissecting a fixed postmortem human brain, preparing smaller tissue blocks for further analysis.
FAQs
Neurons transmit information through electrical impulses and chemical neurotransmitters, allowing signals to pass across interconnected circuits. Glial cells support these networks and help maintain the conditions required for neural activity. This cellular cooperation enables the brain to combine incoming information with ongoing activity, supporting processes such as perception, memory, movement, and decision-making.
Individual brain regions contribute specialized functions, but coordinated behavior depends on communication among them. Interconnected networks allow sensory information to influence movement, emotion, memory, and decisions rather than operating as isolated activities. This network organization also helps explain why disruption in one area or pathway can affect several related functions and produce complex clinical symptoms.
Brain circuits help regulate homeostasis, meaning the stable internal conditions required for normal body function. Their control of vital processes connects neural activity with broader physiological balance. When illness or injury disrupts these regulatory functions, clinicians must consider both neurological changes and their effects on essential body processes when evaluating the patient's condition.
Evaluation can combine clinical examination with neuroimaging and physiological tests. The examination assesses functional changes, while imaging and physiological measurements provide additional information about brain structure or activity. Using these approaches together supports the assessment of stroke, epilepsy, neurodegenerative disease, and traumatic injury, helping clinicians guide diagnosis and select appropriate treatment strategies.
Assessment helps identify how a disorder or injury has affected neural function and can support decisions about treatment. In stroke, epilepsy, neurodegenerative disease, and traumatic injury, clinical findings are interpreted alongside neuroimaging or physiological tests. The resulting information can clarify the nature of impairment, track clinically important changes, and inform efforts to protect or restore function.
Knowledge of brain structure and function helps medicine address situations in which neural activity must be managed or recovered. It informs anesthesia, where brain function is clinically relevant, and rehabilitation, where care aims to support the return or preservation of neural abilities after impairment. This research also contributes to therapies designed to restore or protect neural function.
Mental-health care and neurodegenerative disease research depend on understanding how altered brain networks relate to changes in behavior, cognition, and function. Brain research provides a foundation for connecting these clinical problems with neural mechanisms and for developing therapeutic approaches. It also supports more informed interpretation of examinations, physiological tests, and changes observed over time.