Liver Navigation
Liver Navigation - Related Videos
12:35
In vivo Liver Endocytosis Followed by Purification of Liver Cells by Liver Perfusion
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Cited by 14 •
2011
The study of liver sinusoidal endothelial cells (SECs) must be performed with primary cells obtained from the animal as no cell lines exist. This method relies on liver digestion and differential centrifugation for SEC purification for subsequent culturing and experimentation.
05:19
Practical Methodology of Cognitive Tasks Within a Navigational Assessment
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Cited by 1 •
2015
Children who have complex communication needs can benefit from the use of a speech-generating device (SGD). Cognitive skills were identified as having an impact on the ability to navigate between levels of SGDs. This protocol describes the steps needed for Speech-language Pathologists to assess cognitive skills and navigational abilities.
12:13
Ex Situ Normothermic Machine Perfusion of Donor Livers
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Cited by 21 •
2015
Here we present a protocol describing oxygenated ex situ machine perfusion of donor liver grafts. This article contains a step by step protocol to procure and prepare the liver graft for machine perfusion, prepare the perfusion fluid, prime the perfusion machine and perform oxygenated normothermic machine perfusion of the liver graft.
09:24
Decellularization and Recellularization of Whole Livers
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Cited by 39 •
2011
Perfusion decellularization is a novel technique to produce whole liver scaffolds that retains the organ's extracellular matrix composition and microarchitecture. Herein, the method of preparing whole organ scaffolds using perfusion decellularization and subsequent repopulation with hepatocytes is described. Functional and transplantable liver grafts can be generated using this technique.
08:54
Functional Human Liver Preservation and Recovery by Means of Subnormothermic Machine Perfusion
0 Views •
Cited by 29 •
2015
We describe a method of ex vivo machine perfusion of human liver grafts at subnormothermic temperature (21 °C).
FAQs
Preoperative computed tomography (CT) or magnetic resonance (MR) images provide an anatomical reference, but the liver may move and tissue may change during a procedure. Navigation correlates those images with the patient’s anatomy and uses intraoperative ultrasound to reassess the liver during treatment. This linkage helps clinicians maintain a more accurate target and route during intervention.
These structures serve as important anatomical boundaries when clinicians choose how to reach a lesion or treat it. Liver navigation helps identify the lesion in relation to major vessels and bile ducts, allowing the team to select an access path that limits avoidable contact with important anatomy. The result is more deliberate planning for biopsy, ablation, or resection.
A scan alone describes anatomy before treatment, whereas navigation links that information to the anatomy encountered during the procedure. Because intraoperative ultrasound can account for organ movement and tissue changes, the guidance can be assessed in relation to current conditions. This makes the approach useful when the planned target or access path must be evaluated during treatment.
Clinicians first review CT or MR images to understand the liver and locate the target. They then correlate those images with the patient’s anatomy during treatment, often using intraoperative ultrasound to account for movement and tissue changes. With the lesion and nearby structures identified, they plan or carry out a path for biopsy, tumor ablation, resection, or another guided intervention.
It can support biopsy, tumor ablation, resection, and other image-guided liver interventions. The specific value differs by task: navigation helps locate a lesion for sampling, guide treatment toward a tumor, or support planning for tissue removal. Across these uses, the system supplies anatomical information for choosing a path while helping clinicians consider nearby vessels and bile ducts.
Clinicians can use the information to plan safer, more precise access to a liver lesion and to avoid unnecessary tissue injury where possible. Navigation may also improve procedural planning by connecting lesion location with surrounding anatomy. Its relevance extends across diagnostic and therapeutic interventions because the same guidance principles can support both tissue sampling and treatment.