Operant Training

Operant training is a behavioral learning method in which an individual’s actions become more or less likely according to their consequences, making it important for studying behavior and learning. During training, reinforcement strengthens a desired response, while punishment or the absence of reinforcement can reduce an unwanted response; shaping gradually builds complex behaviors by reinforcing successive approximations. In neuroscience, researchers use controlled cues, responses, and reinforcement schedules to examine reward processing, motivation, decision-making, and the neural circuits underlying learning. Operant training also supports behavioral assessment in animal models and helps link observable performance with changes in brain function.

Operant Training - Related Videos

Research

JoVE Journal - Neuroscience

Operant Sensation Seeking in the Mouse

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Cited by 27 •

2010

In this protocol we describe a method of operant learning using sensory stimuli as a reinforcer in the mouse. It requires no prior training or food restriction, and it allows the study of motivated behavior without the use of a pharmacological or natural reinforcer such as food.

Pavlovian Conditioned Approach Training in Rats

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Cited by 30 •

2016

Here, we present a protocol to elicit Pavlovian conditioned approach behavior in rats. This procedure can be used to measure individual differences in the tendency to approach and attribute incentive salience to reward-related cues and investigate addiction vulnerability.

Research

JoVE Journal - Behavior
Free Sample

Operant Procedures for Assessing Behavioral Flexibility in Rats

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Cited by 69 •

2015

The ability to assess executive functions such as behavioral flexibility in rats is useful for investigating the neurobiology of cognition in both intact animals and disease models. Here we describe automated tasks for assessing strategy shifting and reversal learning, which are particularly sensitive to disruptions in prefrontal cortical networks.

Research

JoVE Journal - Behavior
Free Sample

Quantifying Social Motivation in Mice Using Operant Conditioning

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Cited by 35 •

2015

This article describes a new protocol for the quantitative measurement of social motivation in mice using operant conditioning for a social reward. The protocol is useful for the measurement of social motivation in mouse models of autism and other disorders of social behavior.

Education

JoVE Science Education - Basic Biology

Operating the Glovebox

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2023

Robert M Rioux, Ajay Sathe, Zhifeng Chen, Pennsylvania State University, University Park, PA A glovebox is an isolated enclosure that is designed to maintain an inert atmosphere. The manipulation of chemicals or apparatus is done via the use of gloves, which allow operation while still maintaining an inert atmosphere. A positive pressure is utilized to compensate for any passive leaks. Objects can be transferred in and out of the box using an antechamber that acts as an airlock between the box...

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