Posterior Medial Frontal Cortex
Posterior Medial Frontal Cortex - Related Videos
06:42
Continuous Theta Burst Stimulation of the Posterior Medial Frontal Cortex to Experimentally Reduce Ideological Threat Responses
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Cited by 3 •
2018
Threats reliably evoke shifts in high-level ideological investment, but little work to date has explored the neural mechanisms underlying these dynamics. This paper describes how continuous theta burst transcranial magnetic stimulation may be employed to test the contribution of the posterior medial frontal cortex (and/or other regions) to threat-related ideological shifts.
03:11
Generation of Medial Thalamus-Anterior Cingulate Cortex Slices from Mouse Brains
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2025
The video demonstrates the preparation of medial thalamus-anterior cingulate cortex (MT-ACC) slices from mouse brains. A mouse's brain is dissected, cuts are made to expose the MT-ACC pathway, and slices are generated using a vibratome. The MT-ACC slices are then maintained in oxygenated artificial cerebrospinal fluid.
02:55
Real-Time Calcium Imaging of a Mouse Medial Prefrontal Cortex Using a Miniscope
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2025
Source: Thapa, R., et. al., Stereotaxic Viral Injection and Gradient-Index Lens Implantation for Deep Brain In Vivo Calcium Imaging. J. Vis. Exp. (2021)The video demonstrates real-time calcium imaging using a miniscope in a transduced mouse, correlating neuronal activity with behavior.
09:45
Preparation of Parasagittal Slices for the Investigation of Dorsal-ventral Organization of the Rodent Medial Entorhinal Cortex
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Cited by 36 •
2012
We describe procedures for preparation and electrophysiological recording from brain slices that maintain the dorsal-ventral axis of the medial entorhinal cortex (MEC). Because neural encoding of location follows a dorsal-ventral organization within the MEC, these procedures facilitate investigation of cellular mechanisms important for navigation and memory.
12:30
A Comprehensive Protocol for Manual Segmentation of the Medial Temporal Lobe Structures
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Cited by 33 •
2014
The present work provides a comprehensive set of guidelines for manually tracing the medial temporal lobe (MTL) structures. This protocol can be applied to research involving structural and/or combined structural-functional magnetic resonance imaging (MRI) investigations of the MTL, in both healthy and clinical groups.
FAQs
Activity in the posterior medial frontal cortex becomes especially informative when a task requires selecting among actions or changing an ongoing response. Sensory and task-related information is integrated with current performance demands, allowing activity to support initiation, adjustment, or inhibition. This makes the region relevant to both movement studies and experiments on executive control.
Response conflict and errors reveal when ongoing behavior does not fully match task demands. Because neural activity in the posterior medial frontal cortex changes under these conditions, researchers can examine how the system monitors performance and signals the need for correction. Such observations connect neural activity with behavioral adjustment rather than with action execution alone.
Decision difficulty provides a way to study how cognitive demands alter activity in the posterior medial frontal cortex. More demanding choices can be examined alongside easier decisions to determine how neural responses relate to selection, monitoring, and control. This approach helps connect the region’s activity with attention and executive processes that shape behavior.
Switching or inhibiting behavior requires more than selecting an initial response; it requires monitoring the current plan and modifying it when circumstances change. The posterior medial frontal cortex is relevant to this process because its activity changes when behavioral control must be adjusted. Studying these conditions helps explain how voluntary actions remain flexible rather than proceeding automatically.
Researchers can compare conditions involving voluntary movement, attention, learning, decision difficulty, errors, response conflict, switching, or inhibition. These comparisons focus on how activity changes as cognitive or action demands change. Examining several conditions provides a broader view of how the region links performance monitoring with action planning and executive control.
Studies can relate neural activity to the selection, initiation, adjustment, and monitoring of behavior. They can also examine how attention, learning, and decision demands influence those processes. Together, these outcomes help clarify how voluntary movement and executive control interact, especially when a person must detect an error, resolve conflict, or change a response.
The region is relevant because its activity is associated with decision difficulty, errors, response conflict, and the need to switch or inhibit behavior. These functions connect neural control with both decision-making and motor regulation. Research can therefore use this cortical region to investigate how disrupted cognitive control may relate to difficulties in behavior or movement.