I. Jolanda M. de Vries Department of Medical BioSciences Radboudumc Biography Publications Institution JoVE Articles I. Jolanda M. de Vries has not added a biography. If you are I. Jolanda M. de Vries and would like to personalize this page please email our Author Liaison for assistance. Publications Tailored PGE2 Immunomodulation of MoDCs by Nano-Encapsulated EP2/EP4 Antagonists International Journal of Molecular Sciences. Jan, 2023 | Pubmed ID: 36674907 Intratumoral T Cell Depletion Following Neoadjuvant Chemotherapy in Patients with Muscle-invasive Bladder Cancer is Associated with Poor Clinical Outcome Cancer Immunology, Immunotherapy : CII. Jan, 2023 | Pubmed ID: 35771253 Immunological Responses to Adjuvant Vaccination with Combined CD1c Myeloid and Plasmacytoid Dendritic Cells in Stage III Melanoma Patients Oncoimmunology. 2022 | Pubmed ID: 36524210 Fluorine Labelling of Therapeutic Human Tolerogenic Dendritic Cells for F-magnetic Resonance Imaging Frontiers in Immunology. 2022 | Pubmed ID: 36263039 Tumor Microenvironment Shows an Immunological Abscopal Effect in Patients with NSCLC Treated with Pembrolizumab-radiotherapy Combination Journal for Immunotherapy of Cancer. Oct, 2022 | Pubmed ID: 36252995 Homologous Recombination Repair Deficient Prostate Cancer Represents an Immunologically Distinct Subtype Oncoimmunology. 2022 | Pubmed ID: 35800157 PD-L1 in Gestational Trophoblastic Disease: an Antibody Evaluation Acta Obstetricia Et Gynecologica Scandinavica. Sep, 2022 | Pubmed ID: 35689468 Paired Primary and Metastatic Lesions of Patients with Ipilimumab-treated Melanoma: High Variation in Lymphocyte Infiltration and HLA-ABC Expression Whereas Tumor Mutational Load is Similar and Correlates with Clinical Outcome Journal for Immunotherapy of Cancer. May, 2022 | Pubmed ID: 35550553 Efficient Targeting of NY-ESO-1 Tumor Antigen to Human CDC1s by Lymphotactin Results in Cross-presentation and Antigen-specific T Cell Expansion Journal for Immunotherapy of Cancer. Apr, 2022 | Pubmed ID: 35428705 Metabolomic and Lipidomic Signatures Associated with Activation of Human CDC1 (BDCA3 /CD141 ) Dendritic Cells Immunology. Jan, 2022 | Pubmed ID: 34431087 Assessing the Safety, Tolerability and Efficacy of PLGA-based Immunomodulatory Nanoparticles in Patients with Advanced NY-ESO-1-positive Cancers: a First-in-human Phase I Open-label Dose-escalation Study Protocol BMJ Open. Nov, 2021 | Pubmed ID: 34848513 Whole Blood Transcriptome Profiling Identifies DNA Replication and Cell Cycle Regulation As Early Marker of Response to Anti-PD-1 in Patients with Urothelial Cancer Cancers. Sep, 2021 | Pubmed ID: 34572887 Cisplatin Inhibits Frequency and Suppressive Activity of Monocytic Myeloid-derived Suppressor Cells in Cancer Patients Oncoimmunology. 2021 | Pubmed ID: 34239773 Challenges of Neoantigen Targeting in Lynch Syndrome and Constitutional Mismatch Repair Deficiency Syndrome Cancers. May, 2021 | Pubmed ID: 34067951 Homologous Recombination Repair Deficiency and Implications for Tumor Immunogenicity Cancers. May, 2021 | Pubmed ID: 34067105 A Tipping Point in Cancer-immune Dynamics Leads to Divergent Immunotherapy Responses and Hampers Biomarker Discovery Journal for Immunotherapy of Cancer. May, 2021 | Pubmed ID: 34059522 Immunomodulatory Aged Neutrophils Are Augmented in Blood and Skin of Psoriasis Patients The Journal of Allergy and Clinical Immunology. Oct, 2021 | Pubmed ID: 33745888 PLGA Nanoparticles Co-encapsulating NY-ESO-1 Peptides and IMM60 Induce Robust CD8 and CD4 T Cell and B Cell Responses Frontiers in Immunology. 2021 | Pubmed ID: 33717196 Human Type 1 and Type 2 Conventional Dendritic Cells Express Indoleamine 2,3-dioxygenase 1 with Functional Effects on T Cell Priming European Journal of Immunology. Jun, 2021 | Pubmed ID: 33675038 Response and Survival of Metastatic Melanoma Patients Treated with Immune Checkpoint Inhibition for Recurrent Disease on Adjuvant Dendritic Cell Vaccination Oncoimmunology. Mar, 2020 | Pubmed ID: 33457087 High Health-Related Quality of Life During Dendritic Cell Vaccination Therapy in Patients With Castration-Resistant Prostate Cancer Frontiers in Oncology. 2020 | Pubmed ID: 33194595 Subsets of CD1c DCs: Dendritic Cell Versus Monocyte Lineage Frontiers in Immunology. 2020 | Pubmed ID: 33101275 Prognostic and Predictive Value of Tumor-Infiltrating Immune Cells in Urothelial Cancer of the Bladder Cancers. Sep, 2020 | Pubmed ID: 32967190 Human PDCs Are Superior to CDC2s in Attracting Cytolytic Lymphocytes in Melanoma Patients Receiving DC Vaccination Cell Reports. Jan, 2020 | Pubmed ID: 31995747 Autologous Monocyte-derived DC Vaccination Combined with Cisplatin in Stage III and IV Melanoma Patients: a Prospective, Randomized Phase 2 Trial Cancer Immunology, Immunotherapy : CII. Mar, 2020 | Pubmed ID: 31980913 Multicore Liquid Perfluorocarbon-Loaded Multimodal Nanoparticles for Stable Ultrasound and F MRI Applied to In Vivo Cell Tracking Advanced Functional Materials. May, 2019 | Pubmed ID: 32132881 Blood-derived Dendritic Cell Vaccinations Induce Immune Responses That Correlate with Clinical Outcome in Patients with Chemo-naive Castration-resistant Prostate Cancer Journal for Immunotherapy of Cancer. Nov, 2019 | Pubmed ID: 31727154 Dendritic Cells Require PINK1-Mediated Phosphorylation of BCKDE1α to Promote Fatty Acid Oxidation for Immune Function Frontiers in Immunology. 2019 | Pubmed ID: 31681280 Attacking Tumors From All Sides: Personalized Multiplex Vaccines to Tackle Intratumor Heterogeneity Frontiers in Immunology. 2019 | Pubmed ID: 31040852 The Clinical Application of Cancer Immunotherapy Based on Naturally Circulating Dendritic Cells Journal for Immunotherapy of Cancer. Apr, 2019 | Pubmed ID: 30999964 Early Recurrence in Completely Resected IIIB and IIIC Melanoma Warrants Restaging Prior to Adjuvant Therapy Annals of Surgical Oncology. Nov, 2019 | Pubmed ID: 30830540 PTEN Hamartoma Tumor Syndrome and Immune Dysregulation Translational Oncology. Feb, 2019 | Pubmed ID: 30504085 Health-related Quality of Life Analysis in Stage III Melanoma Patients Treated with Adjuvant Dendritic Cell Therapy Clinical & Translational Oncology : Official Publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico. Jun, 2019 | Pubmed ID: 30465182 Design of Triphasic Poly(lactic--glycolic Acid) Nanoparticles Containing a Perfluorocarbon Phase for Biomedical Applications RSC Advances. Feb, 2018 | Pubmed ID: 35540375 Survival of Ovarian Cancer Patients Is Independent of the Presence of DC and T Cell Subsets in Ascites Frontiers in Immunology. 2018 | Pubmed ID: 30687337 Spontaneous Regression of Ovarian Carcinoma After Septic Peritonitis; A Unique Case Report Frontiers in Oncology. 2018 | Pubmed ID: 30555799 Human Dendritic Cell Subsets Undergo Distinct Metabolic Reprogramming for Immune Response Frontiers in Immunology. 2018 | Pubmed ID: 30455688 Dendritic Cell Cancer Therapy: Vaccinating the Right Patient at the Right Time Frontiers in Immunology. 2018 | Pubmed ID: 30327656 BDCA1+CD14+ Immunosuppressive Cells in Cancer, a Potential Target? Vaccines. Sep, 2018 | Pubmed ID: 30235890 The Potential of In Vivo Imaging for Optimization of Molecular and Cellular Anti-cancer Immunotherapies Molecular Imaging and Biology. 10, 2018 | Pubmed ID: 30030697 Naturally Produced Type I IFNs Enhance Human Myeloid Dendritic Cell Maturation and IL-12p70 Production and Mediate Elevated Effector Functions in Innate and Adaptive Immune Cells Cancer Immunology, Immunotherapy : CII. Sep, 2018 | Pubmed ID: 30019146 Immune Curbing of Cancer Stem Cells by CTLs Directed to NANOG Frontiers in Immunology. 2018 | Pubmed ID: 29971070 Clinically-Applicable Perfluorocarbon-Loaded Nanoparticles For Photoacoustic, F Magnetic Resonance And Fluorescent Imaging Nanotheranostics. 2018 | Pubmed ID: 29868350 Customizing Poly(lactic-co-glycolic Acid) Particles for Biomedical Applications Acta Biomaterialia. Jun, 2018 | Pubmed ID: 29653217 Different Lipid Regulation in Ovarian Cancer: Inhibition of the Immune System International Journal of Molecular Sciences. Jan, 2018 | Pubmed ID: 29342108 Eight-Color Multiplex Immunohistochemistry for Simultaneous Detection of Multiple Immune Checkpoint Molecules Within the Tumor Microenvironment Journal of Immunology (Baltimore, Md. : 1950). Jan, 2018 | Pubmed ID: 29141863 Migrating into the Tumor: a Roadmap for T Cells Trends in Cancer. Nov, 2017 | Pubmed ID: 29120755 Immunotherapy Holds the Key to Cancer Treatment and Prevention in Constitutional Mismatch Repair Deficiency (CMMRD) Syndrome Cancer Letters. Sep, 2017 | Pubmed ID: 28645564 Harnessing RNA Sequencing for Global, Unbiased Evaluation of Two New Adjuvants for Dendritic-cell Immunotherapy Oncotarget. Mar, 2017 | Pubmed ID: 28186996 Innate Lymphoid Cells in Tumor Immunity Biomedicines. Feb, 2016 | Pubmed ID: 28536374 Human Blood Myeloid and Plasmacytoid Dendritic Cells Cross Activate Each Other and Synergize in Inducing NK Cell Cytotoxicity Oncoimmunology. 2016 | Pubmed ID: 27853652 Proteomics of Human Dendritic Cell Subsets Reveals Subset-Specific Surface Markers and Differential Inflammasome Function Cell Reports. Sep, 2016 | Pubmed ID: 27626665 Ipilimumab Administered to Metastatic Melanoma Patients Who Progressed After Dendritic Cell Vaccination Oncoimmunology. Aug, 2016 | Pubmed ID: 27622070 Human CD1c(+) DCs Are Critical Cellular Mediators of Immune Responses Induced by Immunogenic Cell Death Oncoimmunology. Aug, 2016 | Pubmed ID: 27622063 Improving Cancer Immunotherapy by Targeting the STATe of MDSCs Oncoimmunology. Jul, 2016 | Pubmed ID: 27622051 Adjuvant Dendritic Cell Vaccination Induces Tumor-specific Immune Responses in the Majority of Stage III Melanoma Patients Oncoimmunology. Jul, 2016 | Pubmed ID: 27622047 Adjuvant Dendritic Cell Vaccination in High-Risk Uveal Melanoma Ophthalmology. Oct, 2016 | Pubmed ID: 27476772 Expansion of a BDCA1+CD14+ Myeloid Cell Population in Melanoma Patients May Attenuate the Efficacy of Dendritic Cell Vaccines Cancer Research. Aug, 2016 | Pubmed ID: 27325645 Dendritic Cell Vaccination in Melanoma Patients: From Promising Results to Future Perspectives Human Vaccines & Immunotherapeutics. Oct, 2016 | Pubmed ID: 27322496 Immune-related Adverse Events of Dendritic Cell Vaccination Correlate With Immunologic and Clinical Outcome in Stage III and IV Melanoma Patients Journal of Immunotherapy (Hagerstown, Md. : 1997). 2016 | Pubmed ID: 27227325 T-cell Landscape in a Primary Melanoma Predicts the Survival of Patients with Metastatic Disease After Their Treatment with Dendritic Cell Vaccines Cancer Research. Jun, 2016 | Pubmed ID: 27197179 Dendritic Cell-Based Immunotherapy: State of the Art and Beyond Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Apr, 2016 | Pubmed ID: 27084743 Preclinical Exploration of Combining Plasmacytoid and Myeloid Dendritic Cell Vaccination with BRAF Inhibition Journal of Translational Medicine. Apr, 2016 | Pubmed ID: 27075584 Opportunities for Immunotherapy in Microsatellite Instable Colorectal Cancer Cancer Immunology, Immunotherapy : CII. Oct, 2016 | Pubmed ID: 27060000 A Comparative Study of the T Cell Stimulatory and Polarizing Capacity of Human Primary Blood Dendritic Cell Subsets Mediators of Inflammation. 2016 | Pubmed ID: 27057096 Long-lasting Multifunctional CD8 T Cell Responses in End-stage Melanoma Patients Can Be Induced by Dendritic Cell Vaccination Oncoimmunology. 2016 | Pubmed ID: 26942087 Favorable Overall Survival in Stage III Melanoma Patients After Adjuvant Dendritic Cell Vaccination Oncoimmunology. 2016 | Pubmed ID: 26942068 Prophylactic Vaccines Are Potent Activators of Monocyte-derived Dendritic Cells and Drive Effective Anti-tumor Responses in Melanoma Patients at the Cost of Toxicity Cancer Immunology, Immunotherapy : CII. Mar, 2016 | Pubmed ID: 26861670 Effective Clinical Responses in Metastatic Melanoma Patients After Vaccination with Primary Myeloid Dendritic Cells Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. May, 2016 | Pubmed ID: 26712687 Recurrent Candidiasis and Early-onset Gastric Cancer in a Patient with a Genetically Defined Partial MYD88 Defect Familial Cancer. Apr, 2016 | Pubmed ID: 26700889 Primary Human Blood Dendritic Cells for Cancer Immunotherapy-Tailoring the Immune Response by Dendritic Cell Maturation Biomedicines. Dec, 2015 | Pubmed ID: 28536413 Intranodal Vaccination with MRNA-optimized Dendritic Cells in Metastatic Melanoma Patients Oncoimmunology. Aug, 2015 | Pubmed ID: 26405571 Protamine-stabilized RNA As an Ex Vivo Stimulant of Primary Human Dendritic Cell Subsets Cancer Immunology, Immunotherapy : CII. Nov, 2015 | Pubmed ID: 26275446 Multiplex Immunohistochemical Analysis of the Spatial Immune Cell Landscape of the Tumor Microenvironment Mark A. J. Gorris1,2, Evgenia Martynova*1,3, Mark W. D. Sweep*1,4, Iris A. E. van der Hoorn1,5, Shabaz Sultan1,3, Mike J. D. E. Claassens1, Lieke L. van der Woude1,2,6, Kiek Verrijp1,2,6, Carl G. Figdor1,3, Johannes Textor1,3, I. Jolanda M. de Vries1 1Department of Medical BioSciences, Radboudumc, 2Division of Immunotherapy, Oncode Institute, Radboudumc, 3Data Science, Institute for Computing and Information Sciences, Radboud University, 4Department of Medical Oncology, Radboudumc, 5Department of Pulmonary Diseases, Radboudumc, 6Department of Pathology, Radboudumc JoVE 65717 Ricerca sul cancro
Multiplex Immunohistochemical Analysis of the Spatial Immune Cell Landscape of the Tumor Microenvironment Mark A. J. Gorris1,2, Evgenia Martynova*1,3, Mark W. D. Sweep*1,4, Iris A. E. van der Hoorn1,5, Shabaz Sultan1,3, Mike J. D. E. Claassens1, Lieke L. van der Woude1,2,6, Kiek Verrijp1,2,6, Carl G. Figdor1,3, Johannes Textor1,3, I. Jolanda M. de Vries1 1Department of Medical BioSciences, Radboudumc, 2Division of Immunotherapy, Oncode Institute, Radboudumc, 3Data Science, Institute for Computing and Information Sciences, Radboud University, 4Department of Medical Oncology, Radboudumc, 5Department of Pulmonary Diseases, Radboudumc, 6Department of Pathology, Radboudumc JoVE 65717 Ricerca sul cancro