Vera Bonilha Cole Eye Institute, Ophthalmic Research Cleveland Clinic Biography Publications Institution JoVE Articles Vera Bonilha has not added a biography. If you are Vera Bonilha and would like to personalize this page please email our Author Liaison for assistance. Publications NR2E3 Loss Disrupts Photoreceptor Cell Maturation and Fate in Human Organoid Models of Retinal Development The Journal of Clinical Investigation. Apr, 2024 | Pubmed ID: 38652563 Regulated Cell Death Pathways in the Sodium Iodate Model: Insights and Implications for AMD Experimental Eye Research. Jan, 2024 | Pubmed ID: 37972750 A Comparison of Optophysiological Biomarkers of Photoreceptor Stress and Phototoxicity in BALB/cJ, B6 (Cg)-Tyrc-2J/J, and C57Bl/6J Mouse Strains Frontiers in Ophthalmology. 2023 | Pubmed ID: 38689597 Modeling Aging and Retinal Degeneration with Mitochondrial DNA Mutation Burden BioRxiv : the Preprint Server for Biology. Dec, 2023 | Pubmed ID: 38076962 Histological Characterization of Retinal Degeneration in Mucopolysaccharidosis Type IIIC Experimental Eye Research. Apr, 2023 | Pubmed ID: 36858249 Oxidation of DJ-1 Cysteines in Retinal Pigment Epithelium Function International Journal of Molecular Sciences. Sep, 2022 | Pubmed ID: 36077335 CDCP1 Regulates Retinal Pigmented Epithelial Barrier Integrity for the Development of Experimental Autoimmune Uveitis JCI Insight. Sep, 2022 | Pubmed ID: 35951427 Histopathological Assessments Reveal Retinal Vascular Changes, Inflammation, and Gliosis in Patients with Lethal COVID-19 Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Fur Klinische Und Experimentelle Ophthalmologie. Apr, 2022 | Pubmed ID: 34714382 Complementary DNA is Enriched in Atrophic Macular Degeneration and Triggers Retinal Pigmented Epithelium Toxicity Via Cytosolic Innate Immunity Science Advances. Oct, 2021 | Pubmed ID: 34586848 Histopathological Assessments Reveal Retinal Vascular Changes, Inflammation and Gliosis in Patients with Lethal COVID-19 MedRxiv : the Preprint Server for Health Sciences. Feb, 2021 | Pubmed ID: 33655272 A Human Model of Batten Disease Shows Role of CLN3 in Phagocytosis at the Photoreceptor-RPE Interface Communications Biology. Feb, 2021 | Pubmed ID: 33547385 Evidence of Complement Dysregulation in Outer Retina of Stargardt Disease Donor Eyes Redox Biology. Oct, 2020 | Pubmed ID: 33214125 Cellular Changes in Retinas From Patients With Mutations Frontiers in Cell and Developmental Biology. 2020 | Pubmed ID: 33154968 The Retinal Pigment Epithelium in Sorsby Fundus Dystrophy Shows Increased Sensitivity to Oxidative Stress-induced Degeneration Redox Biology. Oct, 2020 | Pubmed ID: 32828705 Oxidative Stress in the Retina and Retinal Pigment Epithelium (RPE): Role of Aging, and DJ-1 Redox Biology. Oct, 2020 | Pubmed ID: 32826201 Retinal Glial and Choroidal Vascular Pathology in Donors Clinically Diagnosed With Stargardt Disease Investigative Ophthalmology & Visual Science. Jul, 2020 | Pubmed ID: 32692840 Geographic Atrophy: Confocal Scanning Laser Ophthalmoscopy, Histology, and Inflammation in the Region of Expanding Lesions Investigative Ophthalmology & Visual Science. Jul, 2020 | Pubmed ID: 32658960 Inhibition of Choroidal Neovascularization by Systemic Delivery of Gold Nanoparticles Nanomedicine : Nanotechnology, Biology, and Medicine. Aug, 2020 | Pubmed ID: 32305594 Neogenin Neutralization Prevents Photoreceptor Loss in Inherited Retinal Degeneration The Journal of Clinical Investigation. Apr, 2020 | Pubmed ID: 32175920 Role of FGF and Hyaluronan in Choroidal Neovascularization in Sorsby Fundus Dystrophy Cells. Mar, 2020 | Pubmed ID: 32143276 Prolonged Ocular Exposure Leads to Retinal Lesions in Mice Experimental Eye Research. Aug, 2019 | Pubmed ID: 31128100 Retinal Angiotensin II and Angiotensin-(1-7) Response to Hyperglycemia and an Intervention with Captopril Journal of the Renin-angiotensin-aldosterone System : JRAAS. 2018 | Pubmed ID: 30126320 Re: Cuenca Et al.: Cellular Characterization of OCT and Outer Retinal Bands Using Specific Immunohistochemistry Markers and Clinical Implications (Ophthalmology. 2018;125;407-422) Ophthalmology. Jul, 2018 | Pubmed ID: 29935676 A Novel Approach for Integrating AF-SLO and SDOCT Imaging Data Demonstrates the Ability to Identify Early Retinal Abnormalities in Mutant Mice and Evaluate the Effects of Genetic and Pharmacological Manipulation Advances in Experimental Medicine and Biology. 2018 | Pubmed ID: 29721941 Oxidative Stress Regulation and DJ-1 Function in the Retinal Pigment Epithelium: Implications for AMD Advances in Experimental Medicine and Biology. 2018 | Pubmed ID: 29721921 The Circadian Clock Gene Bmal1 Controls Thyroid Hormone-Mediated Spectral Identity and Cone Photoreceptor Function Cell Reports. Oct, 2017 | Pubmed ID: 29045837 Absence of DJ-1 Causes Age-related Retinal Abnormalities in Association with Increased Oxidative Stress Free Radical Biology & Medicine. Mar, 2017 | Pubmed ID: 28088625 Retinal Histopathology in Eyes from a Patient with Stargardt Disease Caused by Compound Heterozygous ABCA4 Mutations Ophthalmic Genetics. Jun, 2016 | Pubmed ID: 25265374 Loss of DJ-1 Elicits Retinal Abnormalities, Visual Dysfunction, and Increased Oxidative Stress in Mice Experimental Eye Research. Oct, 2015 | Pubmed ID: 26215528 Retinal Histopathology in Eyes from Patients with Autosomal Dominant Retinitis Pigmentosa Caused by Rhodopsin Mutations Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Fur Klinische Und Experimentelle Ophthalmologie. Dec, 2015 | Pubmed ID: 26202387 The BALB/c Mouse: Effect of Standard Vivarium Lighting on Retinal Pathology During Aging Experimental Eye Research. Jun, 2015 | Pubmed ID: 25895728 Histopathological Comparison of Eyes from Patients with Autosomal Recessive Retinitis Pigmentosa Caused by Novel EYS Mutations Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Fur Klinische Und Experimentelle Ophthalmologie. Feb, 2015 | Pubmed ID: 25491159 Oxidative Stress Regulation by DJ-1 in the Retinal Pigment Epithelium Advances in Experimental Medicine and Biology. 2014 | Pubmed ID: 24664754 Retinal Pigment Epithelium (RPE) Cytoskeleton In vivo and In vitro Experimental Eye Research. Sep, 2014 | Pubmed ID: 24090540 DJ-1-dependent Regulation of Oxidative Stress in the Retinal Pigment Epithelium (RPE) PloS One. 2013 | Pubmed ID: 23844142 Retinal Deimination and PAD2 Levels in Retinas from Donors with Age-related Macular Degeneration (AMD) Experimental Eye Research. Jun, 2013 | Pubmed ID: 23562679 CD40 Induces Anti-Toxoplasma Gondii Activity in Nonhematopoietic Cells Dependent on Autophagy Proteins Infection and Immunity. Jun, 2013 | Pubmed ID: 23509150 Age-related Changes in the Retinal Pigment Epithelium (RPE) PloS One. 2012 | Pubmed ID: 22701690 Imaging Human Postmortem Eyes with SLO and OCT Advances in Experimental Medicine and Biology. 2012 | Pubmed ID: 22183367 Histopathology and Functional Correlations in a Patient with a Mutation in RPE65, the Gene for Retinol Isomerase Investigative Ophthalmology & Visual Science. Oct, 2011 | Pubmed ID: 21931134 Retinal Pathology of a Patient with Goldmann-Favre Syndrome Ophthalmic Genetics. Dec, 2009 | Pubmed ID: 19852574 Age and Disease-related Structural Changes in the Retinal Pigment Epithelium Clinical Ophthalmology (Auckland, N.Z.). Jun, 2008 | Pubmed ID: 19668732 Haze Development After Photorefractive Keratectomy: Mechanical Vs Ethanol Epithelial Removal in Rabbits Journal of Refractive Surgery (Thorofare, N.J. : 1995). Nov, 2008 | Pubmed ID: 19044233 Choroideremia: Analysis of the Retina from a Female Symptomatic Carrier Ophthalmic Genetics. Sep, 2008 | Pubmed ID: 18766988 Retinal Pigment Epithelium Lipofuscin Proteomics Molecular & Cellular Proteomics : MCP. Jul, 2008 | Pubmed ID: 18436525 Age-related Reduction in Retinal Deimination Levels in the F344BN Rat Aging Cell. Jun, 2008 | Pubmed ID: 18248664 Oxidative Damage-induced Inflammation Initiates Age-related Macular Degeneration Nature Medicine. Feb, 2008 | Pubmed ID: 18223656 Semenogelins in the Human Retina: Differences in Distribution and Content Between AMD and Normal Donor Tissues Experimental Eye Research. Jan, 2008 | Pubmed ID: 18036592 Focus on Molecules: Ezrin Experimental Eye Research. Apr, 2007 | Pubmed ID: 16616740 The Retinal Pigment Epithelium Apical Microvilli and Retinal Function Advances in Experimental Medicine and Biology. 2006 | Pubmed ID: 17249618 CRALBP Ligand and Protein Interactions Advances in Experimental Medicine and Biology. 2006 | Pubmed ID: 17249612 Proteomics Implicates Peptidyl Arginine Deiminase 2 and Optic Nerve Citrullination in Glaucoma Pathogenesis Investigative Ophthalmology & Visual Science. Jun, 2006 | Pubmed ID: 16723463 Glucose Utilization by the Retinal Pigment Epithelium: Evidence for Rapid Uptake and Storage in Glycogen, Followed by Glycogen Utilization Experimental Eye Research. Aug, 2006 | Pubmed ID: 16690055 Characterization of Semenogelin Proteins in the Human Retina Experimental Eye Research. Jul, 2006 | Pubmed ID: 16545373 Microvilli Defects in Retinas of Ezrin Knockout Mice Experimental Eye Research. Apr, 2006 | Pubmed ID: 16289046 Abnormal Distribution of Red/green Cone Opsins in a Patient with an Autosomal Dominant Cone Dystrophy Ophthalmic Genetics. Jun, 2005 | Pubmed ID: 16020309 Proteomics Reveal Cochlin Deposits Associated with Glaucomatous Trabecular Meshwork The Journal of Biological Chemistry. Feb, 2005 | Pubmed ID: 15579465 Proteomic Characterization of Isolated Retinal Pigment Epithelium Microvilli Molecular & Cellular Proteomics : MCP. Nov, 2004 | Pubmed ID: 15367653 A Simplified Method for Isolation and Culture of Retinal Pigment Epithelial Cells from Adult Mice Alyssa Hubal1,2, Amelia Pfaff2, Sarah Vos2, Mala Upadhyay3, Vera Bonilha3, Carlos S. Subauste1,2 1Department of Pathology, Case Western Reserve University, 2Division of Infectious Diseases and HIV Medicine, Department of Medicine, Case Western Reserve University, 3Cole Eye Institute, Ophthalmic Research, Cleveland Clinic JoVE 66921 Neuroscienze
A Simplified Method for Isolation and Culture of Retinal Pigment Epithelial Cells from Adult Mice Alyssa Hubal1,2, Amelia Pfaff2, Sarah Vos2, Mala Upadhyay3, Vera Bonilha3, Carlos S. Subauste1,2 1Department of Pathology, Case Western Reserve University, 2Division of Infectious Diseases and HIV Medicine, Department of Medicine, Case Western Reserve University, 3Cole Eye Institute, Ophthalmic Research, Cleveland Clinic JoVE 66921 Neuroscienze
