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Kinetochore-Microtubule Binding in Mitosis
Description
Kinetochore-microtubule binding helps chromosomes line up and separate during mitosis. After the nuclear envelope breaks down, condensed chromosomes are exposed to the bipolar microtubules of the mitotic spindle. The kinetochore is a large, disc-shaped protein complex at the centromere region of each sister chromatid, and it...
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Transcript
Durante la mitosi, in seguito all'assemblaggio di un array di microtubuli bipolari, i microtubuli cinetocore si attaccano ai cromatidi fratelli.
I microtubuli si attaccano a ciascun cromatide tramite il cinetocore situato al centromero. Più microtubuli dello stesso polo del fuso possono legarsi a un singolo cinetocore per formare la fibra...
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